+1 Recommend
0 collections
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Resistance exercise improves muscle strength, health status and pain intensity in fibromyalgia—a randomized controlled trial

      Read this article at

          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.



          Fibromyalgia (FM) is characterized by persistent widespread pain, increased pain sensitivity and tenderness. Muscle strength in women with FM is reduced compared to healthy women. The aim of this study was to examine the effects of a progressive resistance exercise program on muscle strength, health status, and current pain intensity in women with FM.


          A total of 130 women with FM (age 22–64 years, symptom duration 0–35 years) were included in this assessor-blinded randomized controlled multi-center trial examining the effects of progressive resistance group exercise compared with an active control group. A person-centred model of exercise was used to support the participants’ self-confidence for management of exercise because of known risks of activity-induced pain in FM. The intervention was performed twice a week for 15 weeks and was supervised by experienced physiotherapists. Primary outcome measure was isometric knee-extension force (Steve Strong®), secondary outcome measures were health status (FIQ total score), current pain intensity (VAS), 6MWT, isometric elbow-flexion force, hand-grip force, health related quality of life, pain disability, pain acceptance, fear avoidance beliefs, and patient global impression of change (PGIC). Outcomes were assessed at baseline and immediately after the intervention. Long-term follow up comprised the self-reported questionnaires only and was conducted after 13–18 months. Between-group and within-group differences were calculated using non-parametric statistics.


          Significant improvements were found for isometric knee-extension force ( p = 0.010), health status ( p = 0.038), current pain intensity ( p = 0.033), 6MWT ( p = 0.003), isometric elbow flexion force ( p = 0.02), pain disability ( p = 0.005), and pain acceptance ( p = 0.043) in the resistance exercise group ( n = 56) when compared to the control group ( n = 49). PGIC differed significantly ( p = 0.001) in favor of the resistance exercise group at post-treatment examinations. No significant differences between the resistance exercise group and the active control group were found regarding change in self-reported questionnaires from baseline to 13–18 months.


          Person-centered progressive resistance exercise was found to be a feasible mode of exercise for women with FM, improving muscle strength, health status, and current pain intensity when assessed immediately after the intervention.

          Trial registration

          ClinicalTrials.gov identification number: NCT01226784, Oct 21, 2010.

          Related collections

          Most cited references 45

          • Record: found
          • Abstract: found
          • Article: not found

          The prevalence and characteristics of fibromyalgia in the general population.

          To determine the prevalence and characteristics of fibromyalgia in the general population. A random sample of 3,006 persons in Wichita, KS, were characterized according to the presence of no pain, non-widespread pain, and widespread pain. A subsample of 391 persons, including 193 with widespread pain, were examined and interviewed in detail. The prevalence of fibromyalgia was 2.0% (95% confidence interval [95% CI] 1.4, 2.7) for both sexes, 3.4% (95% CI 2.3, 4.6) for women, and 0.5% (95% CI 0.0, 1.0) for men. The prevalence of the syndrome increased with age, with highest values attained between 60 and 79 years (> 7.0% in women). Demographic, psychological, dolorimetry, and symptom factors were associated with fibromyalgia. Fibromyalgia is common in the population, and occurs often in older persons. Characteristic features of fibromyalgia--pain threshold and symptoms--are similar in community and clinic populations, but overall severity, pain, and functional disability are more severe in the clinic population.
            • Record: found
            • Abstract: found
            • Article: not found

            EULAR evidence-based recommendations for the management of fibromyalgia syndrome.

            To develop evidence-based recommendations for the management of fibromyalgia syndrome. A multidisciplinary task force was formed representing 11 European countries. The design of the study, including search strategy, participants, interventions, outcome measures, data collection and analytical method, was defined at the outset. A systematic review was undertaken with the keywords "fibromyalgia", "treatment or management" and "trial". Studies were excluded if they did not utilise the American College of Rheumatology classification criteria, were not clinical trials, or included patients with chronic fatigue syndrome or myalgic encephalomyelitis. Primary outcome measures were change in pain assessed by visual analogue scale and fibromyalgia impact questionnaire. The quality of the studies was categorised based on randomisation, blinding and allocation concealment. Only the highest quality studies were used to base recommendations on. When there was insufficient evidence from the literature, a Delphi process was used to provide basis for recommendation. 146 studies were eligible for the review. 39 pharmacological intervention studies and 59 non-pharmacological were included in the final recommendation summary tables once those of a lower quality or with insufficient data were separated. The categories of treatment identified were antidepressants, analgesics, and "other pharmacological" and exercise, cognitive behavioural therapy, education, dietary interventions and "other non-pharmacological". In many studies sample size was small and the quality of the study was insufficient for strong recommendations to be made. Nine recommendations for the management of fibromyalgia syndrome were developed using a systematic review and expert consensus.
              • Record: found
              • Abstract: not found
              • Article: not found

              Self-efficacy, the exercice of control


                Author and article information

                Arthritis Res Ther
                Arthritis Research & Therapy
                BioMed Central (London )
                18 June 2015
                18 June 2015
                : 17
                : 1
                [ ]Institute of Medicine, Department of Rheumatology and Inflammation research, Sahlgrenska Academy, University of Gothenburg, Guldhedsgatan Box 480, 405 30 Göteborg, Sweden
                [ ]University of Gothenburg Centre for Person Centered Care (GPCC), Göteborg, Sweden
                [ ]Department of Clinical Sciences, Danderyd Hospital, Karolinska Institute, Stockholm, Sweden
                [ ]Department of Dental Medicine, Karolinska Institute, Stockholm, Sweden
                [ ]Sahlgrenska University Hospital, Rheumatology, Göteborg, Sweden
                [ ]Department of Pain and Rehabilitation Center, Linköping University, Linköping, Sweden
                [ ]Department of Medical and Health Sciences, Linköping University, Linköping, Sweden
                [ ]Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
                [ ]Institute of Neuroscience and Physiology, Section of Health and Rehabilitation, Physiotherapy, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden
                © Larsson et al. 2015

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                Research Article
                Custom metadata
                © The Author(s) 2015



                Comment on this article

                Similar content 116

                Cited by 31

                Most referenced authors 1,240