Pituitary secretions and wake-sleep cycle.

Neurohumoral correlations of sleep are considered from three aspects: 1. Metabolism and cerebral blood circulation (CBF, EEG, endocranial pressure, cerebral temperature); 2. Neuromediators and neuropeptides (5-HT, hypnogen neuropeptides); 3. The influence of the sleeping-waking cycle on adeno-hypophyseal secretion rhythms (GH, PRL, LH, TSH). Variations of these parameters can play an important role in the onset of night crises of migraine and cluster headache.