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      Novel structure development of vitamin D-derived photoreactive isomers: development of bone effect enhancement and half-life extension molecules in vivo

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          Abstract

          Towards the development of vitamin D-derived photoreactive isomers in an effort to remove the side effects traditionally associated with vitamin D medicines. Despite the enormous benefits of active vitamin D, its therapeutic application is not without its problems. For instance, the pharmacological doses of active vitamin D required for cancer chemotherapy induce serious side effects, including hypercalcemia (where the calcium level in your blood is above normal) and hyperphosphatemia (where there is an abnormally elevated level of phosphate in the blood). However, it is worth noting that vitamin D supplementation is not a bad thing for humans, as the active vitamin D formation is strictly regulated by blood calcium level, parathyroid hormone and calcitonin.

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          Journal
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          Science Impact, Ltd.
          2398-7073
          December 21 2018
          December 21 2018
          : 2018
          : 10
          : 54-56
          Article
          10.21820/23987073.2018.10.54
          © 2018

          This work is licensed under a Creative Commons Attribution 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

          Earth & Environmental sciences, Medicine, Computer science, Agriculture, Engineering

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