Blog
About

  • Record: found
  • Abstract: found
  • Article: not found

Increased factor XIa levels in patients with a first acute myocardial infarction: the introduction of a new thrombin generation based factor XIa assay.

Read this article at

ScienceOpenPublisherPubMed
Bookmark
      There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

      Abstract

      One of the contributing mechanisms in acute myocardial infarction (AMI) is plasma hypercoagulability. Recently, it was suggested that factor XI activation might play a role in atherothrombosis. To quantify factor XIa plasma levels, we developed a new thrombin generation based assay and hypothesized that in AMI patients factor XIa levels are increased during the acute thrombotic event.

      Related collections

      Author and article information

      Affiliations
      [1 ] Laboratory for Clinical Thrombosis and Haemostasis, Department of Internal Medicine, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, The Netherlands. Electronic address: rinske.loeffen@maastrichtuniversity.nl.
      [2 ] Laboratory for Clinical Thrombosis and Haemostasis, Department of Internal Medicine, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, The Netherlands.
      [3 ] Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands.
      [4 ] Department for Cardiovascular Medicine, Division of Cardiology, University of Münster, Münster, Germany.
      [5 ] Department of Cardiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.
      Journal
      Thromb. Res.
      Thrombosis research
      Elsevier BV
      1879-2472
      0049-3848
      Dec 2014
      : 134
      : 6
      25288467 S0049-3848(14)00500-3 10.1016/j.thromres.2014.09.015

      Comments

      Comment on this article