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      Analysis of the duration of Noravirus shedding among infected kindergarten children during an outbreak

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          Abstract

          Objective To investigate the duration of Norovirus (NoV) shedding among infected school children during a NoV outbreak in a kindergarten, and to provide scientitic basis for epidemic prevention and control.

          Methods Specimens and epidemiological data were collected from suspected cases, and specimens were detected using real-time RT-PCR to determine whether or not infecting with NoV. Specimens were collected every 3-7 days from NoV-infected children until specimens became negative for NoV.

          Results A total of 14 suspected cases were reported, and 12 of them were infected with NoV. The average duration of NoV shedding was (26.58±17.94) d. The specimens among 9 from 12 Nov-infected cases were positive at 7 days, 8 NoV-intected cased remained positive at 14 days and 7 Non-infected cased at least 21 days.

          Conclusion Since NoV shedding duration among NoV-in- fected children tends to longer than their isolation time during outbreaks, reinforcement of hygiene practices among these school children is especially necessary to reduce the risk of virus secondary transmissions after their return to school.

          Abstract

          【摘要】 目的 分析一起托幼机构诺如病毒感染聚集性疫情期间诺如病毒感染者持续排出病毒的情况, 为卫生行政 部门的疫情防控提供科学依据。 方法 以上海市徐汇区发生诺如病毒感染的 1 所托幼机构为研究点, 采用现场流行病学 方法采集疑似病例、密切接触者、环境标本及相关资料, 使用 Read-time RT-PCR 检测标本诺如病毒带毒情况。对诺如病毒 感染者的实验室诊断病例每隔 3~7 d 采样, 直至样本检测阴性。 结果 疫情共报告 14 例急性胃肠炎病例, 其中 12 例实验 室诊断病例平均排毒时间为 (26.58±17.94)d。12 例持续排毒的病例中, 9 例排毒时间超过 7 d, 8 例排毒时间超过14 d, 7 例排毒时间超过 21 d。 结论 感染诺如病毒的儿童排毒时长, 远超其隔离时间。病例返园后仍应加强病例的管理、消毒和 疑似病例的检索工作。

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          Author and article information

          Journal
          CJSH
          Chinese Journal of School Health
          Chinese Journal of School Health (China )
          1000-9817
          01 May 2020
          01 May 2020
          : 41
          : 5
          : 762-764
          Affiliations
          [1] 1Microbiology laboratory, Xuhui Center for Disease Control and Prevention, Shanghai (200237), China
          Author notes
          *Corresponding author: WU Qiangsong, E-mail: wuqs96@ 123456163.com
          Article
          j.cnki.1000-9817.2020.05.034
          10.16835/j.cnki.1000-9817.2020.05.034
          91879fd9-f802-452d-b8cd-00df5e545a07
          © 2020 Chinese Journal of School Health

          This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License (CC BY-NC 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc/4.0/.

          Product
          Self URI (journal-page): http://www.cjsh.org.cn
          Categories
          Journal Article

          Ophthalmology & Optometry,Pediatrics,Nutrition & Dietetics,Clinical Psychology & Psychiatry,Public health
          Enterovirus infections,Disease outbreaks,Time,Child,Epidemiologic studies

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