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      Retrospective pilot study for analysis of antidepressant serum concentrations of citalopram and venlafaxine during inflammation.

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          Abstract

          Inflammation-mediated changes in drug metabolism may increase drug levels in blood and lead to intoxications. The objective of this study was to find out whether elevated serum levels of C-reactive protein (CRP) are associated with increased serum concentrations of the antidepressants citalopram and venlafaxine.

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          Author and article information

          Journal
          Pharmacopsychiatry
          Pharmacopsychiatry
          Georg Thieme Verlag KG
          1439-0795
          0176-3679
          Sep 2015
          : 48
          : 6
          Affiliations
          [1 ] Department of Psychiatry and Psychotherapy, University Medical Centre Mainz, Germany.
          [2 ] Faculty of Pharmacy, Department of Pharmaceutics, University of Mansoura, Egypt.
          [3 ] Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Würzburg, Germany.
          [4 ] Institute of Clinical Chemistry and Laboratory Medicine, University Medical Centre Mainz, Germany.
          Article
          10.1055/s-0035-1559666
          26335759
          919f38c5-26e1-4e95-83e3-0e8dbbd29d99

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