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      Porcine epidemic diarrhoea virus: a comprehensive review of molecular epidemiology, diagnosis, and vaccines

      research-article
      1 , 2 , 3 ,
      Virus Genes
      Springer US
      Porcine epidemic diarrhoea virus, Review, Molecular epidemiology, Diagnosis, Vaccine

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          Abstract

          The porcine epidemic diarrhoea virus (PEDV), a member of the Coronaviridae family, causes acute diarrhoea and dehydration in pigs. Although it was first identified in Europe, it has become increasingly problematic in many Asian countries, including Korea, China, Japan, the Philippines, and Thailand. The economic impacts of the PEDV are substantial, given that it results in significant morbidity and mortality in neonatal piglets and is associated with increased costs related to vaccination and disinfection. Recently, progress has been made in understanding the molecular epidemiology of PEDV, thereby leading to the development of new vaccines. In the current review, we first describe the molecular and genetic characteristics of the PEDV. Then we discuss its molecular epidemiology and diagnosis, what vaccines are available, and how PEDV can be treated.

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          Author and article information

          Contributors
          +82-2-880-1255 , +82-2-885-0263 , parkx026@snu.ac.kr
          Journal
          Virus Genes
          Virus Genes
          Virus Genes
          Springer US (Boston )
          0920-8569
          1572-994X
          22 January 2012
          2012
          : 44
          : 2
          : 167-175
          Affiliations
          [1 ]GRID grid.249967.7, ISNI 0000000406363099, Viral Infectious Disease Research Center, , Korea Research Institute of Bioscience and Biotechnology, ; Daejeon, 305-806 South Korea
          [2 ]GRID grid.412786.e, ISNI 0000000417918264, University of Science and Technology, ; Daejeon, 305-350 South Korea
          [3 ]GRID grid.31501.36, ISNI 0000000404705905, Department of Veterinary Virology, College of Veterinary Medicine and BK21 Program for Veterinary Science, , Seoul National University, ; Seoul, 151-742 Korea
          Article
          713
          10.1007/s11262-012-0713-1
          7089188
          22270324
          919fd4b4-5314-4c47-9292-5ecf4b2f1ee7
          © Springer Science+Business Media, LLC 2012

          This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

          History
          : 9 October 2011
          : 4 January 2012
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          Article
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          © Springer Science+Business Media, LLC 2012

          Microbiology & Virology
          porcine epidemic diarrhoea virus,review,molecular epidemiology,diagnosis,vaccine

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