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      Human Induced Pluripotent Stem Cells as a Platform for Personalized and Precision Cardiovascular Medicine.

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          Abstract

          Human induced pluripotent stem cells (hiPSCs) have revolutionized the field of human disease modeling, with an enormous potential to serve as paradigm shifting platforms for preclinical trials, personalized clinical diagnosis, and drug treatment. In this review, we describe how hiPSCs could transition cardiac healthcare away from simple disease diagnosis to prediction and prevention, bridging the gap between basic and clinical research to bring the best science to every patient.

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          Author and article information

          Journal
          Physiol. Rev.
          Physiological reviews
          American Physiological Society
          1522-1210
          0031-9333
          Jul 2016
          : 96
          : 3
          Affiliations
          [1 ] Stanford Cardiovascular Institute, Department of Medicine, Division of Cardiology, and Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California.
          Article
          96/3/1093
          10.1152/physrev.00036.2015
          27335446

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