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      Positive apraclonidine test 36 hours after acute onset of horner syndrome in dorsolateral pontomedullary stroke.

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          Abstract

          A 40-year-old man developed a Horner syndrome as part of a dorsolateral medullary brainstem infarction. Thirty-six hours after the onset of the stroke, topical instillation of 0.5% apraclonidine produced reversal of anisocoria. This is the first case in which apraclonidine testing has been applied to a patient with a Horner syndrome caused by a lesion in the first segment of the oculosympathetic pathway and the shortest reported interval between clinical manifestations of the lesion and apraclonidine-induced reversal of anisocoria. A review of all reported cases of apraclonidine testing in Horner syndrome suggests that this is a promising diagnostic adjunct that must be validated in larger studies.

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          Author and article information

          Journal
          J Neuroophthalmol
          Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
          Ovid Technologies (Wolters Kluwer Health)
          1536-5166
          1070-8022
          Mar 2010
          : 30
          : 1
          Affiliations
          [1 ] Department of Ophthalmology, Hôpital Delafontaine, Saint-Denis, France. maudjacob@gmail.com
          Article
          00041327-201003000-00005
          10.1097/WNO.0b013e3181b1b41f
          20182200
          92f22b3a-64d6-4338-9678-f3ca3722dc49
          History

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