The aim of this study was to survey the species of large and medium-sized terrestrial mammals occurring at Serra do Brigadeiro State Park (SBSP). Data was compiled from two studies carried out in 2008. Data was collected through sand plots and camera traps. Thirteen species were recorded, one that had not been registered before (Leopardus wiedii) and one exotic (Canis lupus familiaris). Species richness estimate for camera trapping was 13.53±1.75. For the sand plots, estimate was lower (9±1.73 species). The low number of inventories focusing on large and medium-sized terrestrial mammals in the Mantiqueira region of the Atlantic forest and the presence of the domestic dogs within the Park limits emphasizes the need for monitoring programs to identify the major threats to preserved areas in the region.