Effectiveness and acceptability of deep brain stimulation (DBS) of the subgenual cingulate cortex for treatment-resistant depression: a systematic review and exploratory meta-analysis.

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Abstract

Deep brain stimulation (DBS) applied to the subgenual cingulate cortex (SCC) has been recently investigated as a potential treatment for severe and chronic treatment-resistant depression (TRD). Given its invasive and experimental nature, a comprehensive evaluation of its effectiveness and acceptability is of paramount importance. Therefore, we conducted the present systematic review and exploratory meta-analysis.

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Journal ID (iso-abbrev): J Affect Disord

Title: Journal of affective disorders

Publisher: Elsevier BV

ISSN (Electronic): 1573-2517

ISSN (Print): 0165-0327

Publication date (Electronic): Apr 2014

Volume: 159

Affiliations

[1 ] Neuromodulation Research Clinic, Douglas Mental Health University Institute and McGill University, Montréal, Québec, Canada; Depressive Disorders Program, Douglas Mental Health University Institute and McGill University, Montréal, Québec, Canada. Electronic address: nrc.douglas@me.com.

[2 ] Department of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.

[3 ] Neuromodulation Research Clinic, Douglas Mental Health University Institute and McGill University, Montréal, Québec, Canada.

[4 ] Neuromodulation Research Clinic, Douglas Mental Health University Institute and McGill University, Montréal, Québec, Canada; Depressive Disorders Program, Douglas Mental Health University Institute and McGill University, Montréal, Québec, Canada.

[5 ] Department of Psychiatry, Toronto General Hospital, University Health Network, Toronto, Canada.

Article

Publisher Item ID: S0165-0327(14)00054-8

DOI: 10.1016/j.jad.2014.02.016

PubMed ID: 24679386

SO-VID: 93578157-d812-453e-a0d0-a02521895182

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Keywords: Acceptability,Deep brain stimulation,Effectiveness,Treatment-resistant depression

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Keywords: Acceptability, Deep brain stimulation, Effectiveness, Treatment-resistant depression

Effectiveness and acceptability of deep brain stimulation (DBS) of the subgenual cingulate cortex for treatment-resistant depression: a systematic review and exploratory meta-analysis.

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Karger: Neurology and Neuroscience

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