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      A Review of the Diagnosis and Treatment of Atlantoaxial Dislocations

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          Abstract

          Study Design Literature review.

          Objective Atlantoaxial dislocation (AAD) is a rare and potentially fatal disturbance to the normal occipital-cervical anatomy that affects some populations disproportionately, which may cause permanent neurologic deficits or sagittal deformity if not treated in a timely and appropriate manner. Currently, there is a lack of consensus among surgeons on the best approach to diagnose, characterize, and treat this condition. The objective of this review is to provide a comprehensive review of the literature to identify timely and effective diagnostic techniques and treatment modalities of AAD.

          Methods This review examined all articles published concerning “atlantoaxial dislocation” or “atlantoaxial subluxation” on the PubMed database. We included 112 articles published between 1966 and 2014.

          Results Results of these studies are summarized primarily as defining AAD, the normal anatomy, etiology of dislocation, clinical presentation, diagnostic techniques, classification, and recommendations for timely treatment modalities.

          Conclusions The Wang Classification System provides a practical means to diagnose and treat AAD. However, future research is required to identify the most salient intervention component or combination of components that lead to the best outcomes.

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          Most cited references90

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          Posterior C1-C2 fusion with polyaxial screw and rod fixation.

          A novel technique of atlantoaxial stabilization using individual fixation of the C1 lateral mass and the C2 pedicle with minipolyaxial screws and rods is described. In addition, the initial results of this technique on 37 patients are described. To describe the technique and the initial clinical and radiographic results for posterior C1-C2 fixation with a new implant system. Stabilization of the atlantoaxial complex is a challenging procedure because of the unique anatomy of this region. Fixation by transarticular screws combined with posterior wiring and structural bone grafting leads to excellent fusion rates. The technique is technically demanding and has a potential risk of injury to the vertebral artery. In addition, this procedure cannot be used in the presence of fixed subluxation of C1 on C2 and in the case of an aberrant path of the vertebral artery. To address these limitations, a new technique of C1-C2 fixation has been developed: bilateral insertion of polyaxial-head screws in the lateral mass of C1 and through the pars interarticularis into the pedicle of C2, followed by a fluoroscopically controlled reduction maneuver and rod fixation. After posterior exposure of the C1-C2 complex, the 3.5-mm polyaxial screws are inserted in the lateral masses of C1. Two polyaxial screws are then inserted into the pars interarticularis of C2. Drilling is guided by anatomic landmarks and fluoroscopy. If necessary, reduction of C1 onto C2 can be accomplished by manipulation of the implants, followed by fixation to the 3-mm rod. For definitive fusion, cancellous bone can be added. No structural bone graft or wiring is required. In selected cases, e.g., C1-C2 subluxation or fractures in young patients in whom only temporary fixation is necessary, the instrumentation can be removed after an appropriate time. Because the joint surfaces stay intact, the patient can regain motion in the C1-C2 joints. Thirty-seven patients underwent this procedure. No neural or vascular damage related to this technique has been observed. The early clinical and radiologic follow-up data indicate solid fusion in all patients. Fixation of the atlantoaxial complex using polyaxial-head screws and rods seems to be a reliable technique and should be considered an efficient alternative to the previously reported techniques.
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            Transpedicular screw fixation for traumatic lesions of the middle and lower cervical spine: description of the techniques and preliminary report.

            Thirteen patients with fractures and/or dislocations of the middle and lower cervical spine were treated by transpedicular screw fixation using the Steffee variable screw placement system. Postoperative immobilization was either not used or simplified to short-term use of a soft neck collar. Recovery of nerve function and correction of kyphotic and/or translational deformities were satisfactory. All patients had solid fusion without loss of correction at the latest follow-up. There were no neurovascular complications. It was concluded that transpedicular screw fixation is as strong a fixation procedure for the cervical spine as it is for the thoracic and lumbar spine. This surgical procedure is associated with some risks of major neurovascular injuries; however, safety is adequate if the procedure is performed by experienced surgeons using meticulous surgical techniques.
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              Posterior C2 fixation using bilateral, crossing C2 laminar screws: case series and technical note.

              Rigid screw fixation of the axis, for either atlantoaxial fixation or for incorporation of C2 into subaxial cervical constructs, provides significant stability and excellent long-term fusion results but remains technically demanding due to the danger of injury to the vertebral artery. Anatomic variability of the foramen transversarium in the body of the axis can preclude safe transarticular C1-C2 screw placement in up to 20% of patients. Although more recent methods of C2 screw fixation with pedicle screws allow safer fixation in a higher number of patients, there remains a significant risk to the vertebral artery with C2 pedicle screw placement. The author describes a novel technique of C2 rigid screw fixation using bilateral, crossing C2 laminar screws, not previously reported in the literature, which does not place the vertebral artery at risk during C2 fixation. This technique has been successfully used by the author in cases of craniocervical and atlantoaxial fixation as well as for incorporation of C2 into subaxial fixations. The technique is illustrated, and the author's initial experience in treating 10 patients with crossing, bilateral C2 aminar screws for indications of trauma, neoplasm, pseudarthrosis, and degenerative disease is reviewed. The possible advantages of C2 fixation with C2 laminar screws are discussed.
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                Author and article information

                Journal
                Global Spine J
                Global Spine J
                10.1055/s-00000177
                Global Spine Journal
                Georg Thieme Verlag KG (Stuttgart · New York )
                2192-5682
                2192-5690
                22 May 2014
                August 2014
                : 4
                : 3
                : 197-210
                Affiliations
                [1 ]Division of Spinal Surgery, Department of Orthopaedic Surgery, NYU Medical Center Hospital for Joint Diseases, NYU School of Medicine, New York, New York, United States
                [2 ]Orthopaedic Department, Peking University Third Hospital, Beijing, China
                Author notes
                Address for correspondence Peter G. Passias, MD New York Spine Institute 361 Merrick Avenue, Westbury, NY 11590United States Peter.Passias@ 123456nyumc.org pgpassias@ 123456yahoo.com
                Article
                1300057
                10.1055/s-0034-1376371
                4111952
                25083363
                939db139-6670-45a9-87f1-b6401ddf3cc1
                © Thieme Medical Publishers
                History
                : 20 August 2013
                : 15 April 2014
                Categories
                Article

                atlantoaxial dislocation,atlantoaxial subluxation,comprehensive review,classification,diagnosis,treatment

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