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      Sequencing for Surveillance of Emerging Infectious Diseases: from Laboratory to Field

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          The potential of whole genome NGS for infectious disease diagnosis.

          Non-targeted identification of microbes is now possible directly in biological samples, based on whole-genome-NGS (WG-NGS) techniques that allow deep sequencing of nucleic acids, data mining and sorting out of sequences of pathogens without any a priori hypothesis. WG-NGS was first only used as a research tool due to its cost, complexity and lack of standardization. Recent improvements in sample preparation and bioinformatics pipelines and decrease in cost now allow actionable diagnostics in patients. The potency and limits of WG-NGS and possible future indications are discussed here. WG-NGS will likely soon become a standard procedure in microbiological diagnosis.
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            Unexpected and Rapid Spread of Zika Virus in The Americas—Implications for Public Health Preparedness for Mass Gatherings at the 2016 Brazil Olympic Games

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              Real-time, portable genome sequencing for Ebola surveillance

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                Author and article information

                Contributors
                Journal
                Infectious Diseases and Translational Medicine
                Infect. Dis. Transl. Med.
                Infect. Dis. Transl. Med.
                International Biological and Medical Journals Publishing House Co., Limited (Room E16, 3/f, Yongda Commercial Building, No.97, Bonham Stand (Sheung Wan), HongKong )
                2411-2917
                10 April 2016
                10 April 2016
                : 2
                : 1
                : 1-2
                Affiliations
                From the Department of Anatomy and Physiology, Kansas State University, 228 Coles Hall, Manhattan, KS, USA66506-5802
                From the Department of Anatomy and Physiology, Kansas State University, 228 Coles Hall, Manhattan, KS, USA66506-5802
                Author notes
                Correspondence to: Lihua Wang, Email: wanglih9755@ 123456hotmail.com ;
                Jishu Shi, Email: jishushi@ 123456gmail.com .
                Article
                10.11979/idtm.201601001
                93a5e832-b410-41e5-a124-7d267c567dc8

                This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

                Page count
                Figures: 0, Tables: 0, References: 5, Pages: 2
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                Medicine,Infectious disease & Microbiology
                Medicine, Infectious disease & Microbiology

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