Solvents and metals are used in many production processes and the problem of the deposition of residual solvents and metals on the aquifer system or on soils is very relevant. Legislation is the primary tool for regulating the highest permissible concentrations of pollutants and the European Union policy is very restrictive, so to adhere to it utilising sustainable technologies is a must. Moreover, due to the development and widespread usage of pharmaceuticals, some of these molecules are appearing in urban and rural wastewater, constituting a new class of emergent pollutants that also need to be tackled. Developing sustainable solutions to address this major challenge is critical. The RehaBioSys project aims to define and optimise a designed-to-target supported biomass, as in a biofilm, that allows in-situ regeneration and may be able to retain or to degrade some specific molecules considered as pollutants even at low concentrations.The research project is led by Professor Teresa Tavares, based at the Biological Engineering Centre at the University of Minho, Portugal.