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      Analyzing the chance of developing dementia among geriatric people: a cross-sectional pilot study in Bangladesh : Analyzing the chance of dementia

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          Abstract

          Alzheimer's disease is the most common form of dementia, representing 60-80% of cases, and ageing is the primary risk factor for the development of Alzheimer's disease. The objective of this study was to examine the chance of developing dementia (i.e. mild cognitive impairment (MCI), Alzheimer's disease) among geriatric people in Bangladesh.

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          Most cited references34

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          The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis.

          R M Sapolsky, L Krey, B S McEwen (1986)
          Article 0 comments Cited 300 times – based on 0 reviews     Review now
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            Alzheimer's disease

            Elizabeth Burns, S Iliffe (2009)
            Article 0 comments Cited 228 times – based on 0 reviews     Review now
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              Why women have more Alzheimer's disease than men: gender and mitochondrial toxicity of amyloid-beta peptide.

              Ana Lloret, Jose Viña (2009)
              The main risk factors for developing Alzheimer's disease (AD) are age and gender. The incidence of the disease is higher in women than in men, and this cannot simply be attributed to the higher longevity of women versus men. Thus, there must be a specific pathogenic mechanism to explain the higher incidence of AD cases in women. In this regard, it is notable that mitochondria from young females are protected against amyloid-beta toxicity, generate less reactive oxygen species, and release less apoptogenic signals than those from males. However, all this advantage is lost in mitochondria from old females. Since estrogenic compounds protect against mitochondrial toxicity of amyloid-beta, estrogenic action may be important in protecting cells from amyloid-beta toxicity and suggests a possible treatment or prevention strategy for AD. Unfortunately, to date, clinical trials with Ginkgo biloba and other estrogenic therapies have not proved successful in treating AD. As such, more experiments and clinical trials are indeed warranted to find conditions in which estrogenic compounds may be useful to prevent or treat AD.
              Article 0 comments Cited 162 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Title: Psychogeriatrics
                Abbreviated Title: Psychogeriatrics
                Publisher: Wiley
                ISSN: 13463500
                Publication date (Electronic): September 16 2018
                Affiliations
                [1 ]Department of Pharmacy; Southeast University; Dhaka Bangladesh
                [2 ]Department of Clinical Psychology; Tottori University Graduate School of Medical Sciences; Tottori Japan
                [3 ]Department of Pharmacy; Noakhali Science and Technology University; Noakhali Bangladesh
                [4 ]Department of Pharmacy; East West University; Dhaka Bangladesh
                Article
                DOI: 10.1111/psyg.12368
                PubMed ID: 30221441
                SO-VID: 94bbfb32-e63e-4326-ba73-7c342ab7e4e2
                Copyright © © 2018
                License:

                http://doi.wiley.com/10.1002/tdm_license_1.1

                http://onlinelibrary.wiley.com/termsAndConditions#vor

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