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      The kINPen—a review on physics and chemistry of the atmospheric pressure plasma jet and its applications

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          Most cited references294

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          Gas Discharge Physics

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            Fluorescence probes used for detection of reactive oxygen species.

            Endogenously produced pro-oxidant reactive species are essential to life, being involved in several biological functions. However, when overproduced (e.g. due to exogenous stimulation), or when the levels of antioxidants become severely depleted, these reactive species become highly harmful, causing oxidative stress through the oxidation of biomolecules, leading to cellular damage that may become irreversible and cause cell death. The scientific research in the field of reactive oxygen species (ROS) associated biological functions and/or deleterious effects is continuously requiring new sensitive and specific tools in order to enable a deeper insight on its action mechanisms. However, reactive species present some characteristics that make them difficult to detect, namely their very short lifetime and the variety of antioxidants existing in vivo, capable of capturing these reactive species. It is, therefore, essential to develop methodologies capable of overcoming this type of obstacles. Fluorescent probes are excellent sensors of ROS due to their high sensitivity, simplicity in data collection, and high spatial resolution in microscopic imaging techniques. Hence, the main goal of the present paper is to review the fluorescence methodologies that have been used for detecting ROS in biological and non-biological media.
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              The atmospheric-pressure plasma jet: a review and comparison to other plasma sources

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                Author and article information

                Journal
                Journal of Physics D: Applied Physics
                J. Phys. D: Appl. Phys.
                IOP Publishing
                0022-3727
                1361-6463
                June 13 2018
                June 13 2018
                May 16 2018
                : 51
                : 23
                : 233001
                Article
                10.1088/1361-6463/aab3ad
                94fe8e68-c46e-4df7-9b72-cb5bba6c4be8
                © 2018

                http://iopscience.iop.org/info/page/text-and-data-mining

                http://creativecommons.org/licenses/by/3.0/


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