Investigation of new cancer diagnosis using non-Gaussian diffusion MRI and IVIM

Abstract

MR images, using a complex variety of techniques, make it possible to obtain information and image contrast of various patterns that cannot be obtained with other techniques. In particular, diffusion MRI allows information to be obtained in submillimetres although images are acquired in millimeters, and reflects the specific tissue structure of tumor, using the quantitative value Apparent Diffusion Coefficient (ADC). This has been shown to be a useful biomarker for differentiaitng malignant and benign tumours, tumor grades or prognostic factors. A team at Kyoto University Hospital is developing a new approach that utilises diffusion MRI to provide a non-invasive alternative to the current procedures, and its standardzaion for this new approach become available at clinical practice.