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      Treatment choice of immunotherapy or further chemotherapy for Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis.

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          Abstract

          Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis (EBV-HLH) leads to an aggressive and often fatal course without appropriate treatment. Etoposide therapy is crucial for the better prognosis, although it remains unknown what patients need cytotoxic agents. Since we have complied with step-up strategy in a tertiary center, treatment outcomes were studied to search predictors for disease course.

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          Author and article information

          Journal
          Pediatr Blood Cancer
          Pediatric blood & cancer
          Wiley
          1545-5017
          1545-5009
          Aug 2012
          : 59
          : 2
          Affiliations
          [1 ] Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
          Article
          10.1002/pbc.24039
          22183955
          9522291c-f0a4-492d-abad-98670186a18d
          History

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