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      Monolithic Microwave-Microfluidic Sensors Made with Low Temperature Co-Fired Ceramic (LTCC) Technology

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          Abstract

          This paper compares two types of microfluidic sensors that are designed for operation in ISM (Industrial, Scientific, Medical) bands at microwave frequencies of 2.45 GHz and 5.8 GHz. In the case of the first sensor, the principle of operation is based on the resonance phenomenon in a microwave circuit filled with a test sample. The second sensor is based on the interferometric principle and makes use of the superposition of two coherent microwave signals, where only one goes through a test sample. Both sensors are monolithic structures fabricated using low temperature co-fired ceramics (LTCCs). The LTCC-based microwave-microfluidic sensor properties are examined and compared by measuring their responses for various concentrations of two types of test fluids: one is a mixture of water/ethanol, and the other is dopamine dissolved in a buffer solution. The experiments show a linear response for the LTCC-based microwave-microfluidic sensors as a function of the concentration of the components in both test fluids.

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          Most cited references29

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          Optical sensing systems for microfluidic devices: a review.

          This review deals with the application of optical sensing systems for microfluidic devices. In the "off-chip approach" macro-scale optical infrastructure is coupled, while the "on-chip approach" comprises the integration of micro-optical functions into microfluidic devices. The current progress of the use of both optical sensing approaches in microfluidic devices, as well as its applications is described. In all cases, sensor size and shape profoundly affect the detection limits, due to analyte transport limitation, not to signal transduction limitation. The micro- or nanoscale sensors are limited to picomolar-order detection for practical time scales. The review concludes with an assessment of future directions of optical sensing systems for integrated microfluidic devices.
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            Metamaterial-based microfluidic sensor for dielectric characterization

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              Novel Microwave Microfluidic Sensor Using a Microstrip Split-Ring Resonator

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                Author and article information

                Journal
                Sensors (Basel)
                Sensors (Basel)
                sensors
                Sensors (Basel, Switzerland)
                MDPI
                1424-8220
                30 January 2019
                February 2019
                : 19
                : 3
                : 577
                Affiliations
                [1 ]Faculty of Microsystem Electronics and Photonics, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland; laura.jasinska@ 123456pwr.edu.pl
                [2 ]Faculty of Electronics, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland; anna.grytsko@ 123456pwr.edu.pl (A.G.); piotr.slobodzian@ 123456pwr.edu.pl (P.S.)
                [3 ]Faculty of Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland; kamila.drzozga@ 123456pwr.edu.pl (K.D.); joanna.cabaj@ 123456pwr.edu.pl (J.C.)
                Author notes
                [* ]Correspondence: karol.malecha@ 123456pwr.edu.pl ; Tel.: +48-71-320-4955
                Author information
                https://orcid.org/0000-0002-2240-0326
                Article
                sensors-19-00577
                10.3390/s19030577
                6386962
                30704068
                9524179c-aaed-47b9-af39-cd7fc0b2b549
                © 2019 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 02 January 2019
                : 28 January 2019
                Categories
                Article

                Biomedical engineering
                microwaves,microfluidic,sensor,ltcc
                Biomedical engineering
                microwaves, microfluidic, sensor, ltcc

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