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      Endothelial cell functions.¶Relationship to atherogenesis

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      Basic Research in Cardiology
      Springer Science and Business Media LLC

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          Abstract

          The vascular endothelium plays a critical role in the preservation of normal vessel wall structure and function. In particular, endothelial cells control vascular permeability, vessel tone, coagulation, fibrinolysis, and inflammatory responses. These functions are accomplished by production of a variety of biologically active substances. However, endothelial cell-mediated reactions may also lead to the development of pathological stages within the vessel wall. The current review is focused on endothelial cell metabolism in relationship to the development of atherosclerosis.

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          Author and article information

          Journal
          395
          Basic Research in Cardiology
          Basic Research in Cardiology
          Springer Science and Business Media LLC
          0300-8428
          1435-1803
          September 1 1999
          September 1 1999
          : 94
          : 5
          : 295-314
          Article
          10.1007/s003950050156
          10543305
          95d62adc-8ff5-4a75-b4a8-e5a19a9ce57e
          © 1999

          http://www.springer.com/tdm

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