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      Tear film breakup and structure studied by simultaneous video recording of fluorescence and tear film lipid layer images.

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          Abstract

          The thinning of the precorneal tear film between blinks and tear film breakup can be logically analyzed into contributions from three components: evaporation, flow into the cornea, and tangential flow along the corneal surface. Whereas divergent tangential flow contributes to certain types of breakup, it has been argued that evaporation is the main cause of tear thinning and breakup. Because evaporation is controlled by the tear film lipid layer (TFLL) it should therefore be expected that patterns of breakup should match patterns in the TFLL, and this hypothesis is tested in this study.

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          Author and article information

          Journal
          Invest Ophthalmol Vis Sci
          Investigative ophthalmology & visual science
          Association for Research in Vision and Ophthalmology (ARVO)
          1552-5783
          0146-0404
          Jul 22 2013
          : 54
          : 7
          Affiliations
          [1 ] College of Optometry, The Ohio State University, Columbus, Ohio 43210, USA. King-smith.1@osu.edu
          Article
          iovs.13-11878
          10.1167/iovs.13-11878
          3720150
          23766476
          9623674a-334a-404d-9231-503ca2ad82dd
          History

          evaporation,fluorescein breakup,hyperosmolarity,tear film lipid layer

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