Guidance for RNA-seq co-expression network construction and analysis: safety in numbers.

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Abstract

RNA-seq co-expression analysis is in its infancy and reasonable practices remain poorly defined. We assessed a variety of RNA-seq expression data to determine factors affecting functional connectivity and topology in co-expression networks.

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Journal

Journal ID (iso-abbrev): Bioinformatics

Title: Bioinformatics (Oxford, England)

Publisher: Oxford University Press (OUP)

ISSN (Electronic): 1367-4811

ISSN (Print): 1367-4803

Publication date (Electronic): Jul 01 2015

Volume: 31

Issue: 13

Affiliations

[1 ] Stanley Institute for Cognitive Genomics, Cold Spring Harbor Laboratory, 500 Sunnyside Boulevard Woodbury, NY 11797, USA.

Article

Publisher Item ID: btv118

DOI: 10.1093/bioinformatics/btv118

PubMed ID: 25717192

SO-VID: 962c18da-2035-4504-a7c4-ea1e4423d362

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