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      Manifestaciones articulares en la acromegalia: implicaciones diagnósticas y terapéuticas de la coexistencia de la artropatía acromegálica y artritis reumatoide Translated title: Articular manifestations in acromegaly: diagnostic and therapeutic implications of the coexistence of acromegalic arthropathy and rheumatoid arthritis

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      Anales del Sistema Sanitario de Navarra
      Gobierno de Navarra. Departamento de Salud
      Artritis reumatoide, Artropatía acromegálica, Artritis, Artralgia, Acromegalia, Rheumatoid arthritis, Acromegalic arthropathy, Arthritis, Arthralgia, Acromegaly

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          Resumen

          La presencia de artropatía en los pacientes con acromegalia puede ser debida a la recurrencia de la acromegalia o a la existencia de una enfermedad articular inflamatoria como la artritis reumatoide (AR). Existen pocas publicaciones que evalúen la coexistencia de AR y acromegalia. La presentación de dos casos con la coexistencia de AR y artropatía acromegálica permite evaluar las claves para su diagnóstico diferencial y sus implicaciones en el tratamiento. El diagnóstico de AR en los pacientes con acromegalia requiere de una alta sospecha clínica, por lo que debería ser considerado en aquellos casos en los que no se consiga un adecuado control de los síntomas. El retraso en el diagnóstico y tratamiento de la AR puede incrementar el daño articular y posiblemente empeora el pronóstico funcional de los pacientes.

          Abstract

          The presence of arthropathy in patients with acromegaly may suggest recurrence of acromegaly or the existence of an inflammatory joint disease such as rheumatoid arthritis (RA). Few publications have evaluated the coexistence of RA and acromegaly. Two cases were presented with a coexistence of RA and acromegalic arthopathy, which enabled us to evaluate the key factors in differential diagnoses and the implications for treatment. Diagnosis of RA in patients with acromegaly requires a high level of clinical suspicion, and should therefore be considered in cases where adequate symptom control is not achieved. Delay in the diagnosis and treatment of RA can increase joint damage and possibly worsen a patient’s functional prognosis.

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          Most cited references19

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          Arthropathy in acromegaly.

          Articular involvement in acromegaly is one of the most frequent clinical complications and may be present as the earliest symptom in a significant proportion of patients. The involvement of other organs may be of clinical importance and contribute to increased morbidity and mortality of patients suffered from acromegaly. Early diagnosis and proper treatment of the diseases can prevent the development of irreversible complications of the disease and improve the quality of life in patients suffering from the disease. Copyright © 2010 Elsevier Inc. All rights reserved.
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            Progression of acromegalic arthropathy despite long-term biochemical control: a prospective, radiological study.

            Arthropathy is an invalidating complication of acromegaly, of which the prognosis and determinants are currently unknown in treated acromegaly. Therefore, the objective of the present study was to investigate the radiographic progression of arthropathy over a mean follow-up period of 2.6 years and determinants of outcome in patients with long-term, well-controlled acromegaly.
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              Acromegalic arthropathy

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                Author and article information

                Journal
                An Sist Sanit Navar
                An Sist Sanit Navar
                assn
                Anales del Sistema Sanitario de Navarra
                Gobierno de Navarra. Departamento de Salud
                1137-6627
                2340-3527
                12 April 2021
                May-Aug 2021
                : 44
                : 1
                : 97-105
                Affiliations
                [1] originalServicio de Reumatología. Hospital General Regional número 1. Delegación Yucatán. Instituto Mexicano del Seguro Social. Mérida. México. normalizedInstituto Mexicano del Seguro Social orgdiv2Servicio de Reumatología. Hospital General Regional número 1 orgdiv1Delegación Yucatán orgnameInstituto Mexicano del Seguro Social Mérida, Mexico
                Author notes
                [Correspondencia: ] Gabriel Horta-Baas, Calle 41, número 439 x 34, Colonia Industrial, 97150, Mérida (Yucatán), México. E-mail: gabho@ 123456hotmail.com
                Article
                10.23938/ASSN.0928
                10019543
                33853222
                962e0a82-8555-44b6-b250-05c25a8e4e83

                Este es un artículo publicado en acceso abierto bajo una licencia Creative Commons

                History
                : 30 September 2020
                : 30 October 2020
                : 09 December 2020
                Page count
                Figures: 3, Tables: 1, Equations: 0, References: 18, Pages: 09
                Categories
                Notas Clínicas

                artritis reumatoide,artropatía acromegálica,artritis,artralgia,acromegalia,rheumatoid arthritis,acromegalic arthropathy,arthritis,arthralgia,acromegaly

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