Adenosine induces cell-cycle arrest and apoptosis in androgen-dependent and -independent prostate cancer cell lines, LNcap-FGC-10, DU-145, and PC3.

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Abstract

Adenosine has been shown to inhibit cell growth and induce apoptosis in the several cancer cells via intrinsic and extrinsic pathway. The present study was designed to understand the mechanism underlying adenosine-induced apoptosis in the DU-145, PC3, and LNcap-FGC10 human prostate cancer cells.

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Journal

Journal ID (iso-abbrev): Prostate

Title: The Prostate

ISSN (Electronic): 1097-0045

ISSN (Print): 0270-4137

Publication date (Electronic): Mar 2012

Volume: 72

Issue: 4

Affiliations

[1 ] Department of Clinical Biochemistry, Cancer Research Laboratory, School of Medical Science, Tarbiat Modares University, Tehran, Iran.

Article

DOI: 10.1002/pros.21438

PubMed ID: 21656837

SO-VID: 963d4708-0554-42f2-b5e3-13067a982675

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