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      International Journal of Nanomedicine (submit here)

      This international, peer-reviewed Open Access journal by Dove Medical Press focuses on the application of nanotechnology in diagnostics, therapeutics, and drug delivery systems throughout the biomedical field. Sign up for email alerts here.

      105,621 Monthly downloads/views I 7.033 Impact Factor I 10.9 CiteScore I 1.22 Source Normalized Impact per Paper (SNIP) I 1.032 Scimago Journal & Country Rank (SJR)

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      Biomimetics: forecasting the future of science, engineering, and medicine

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          Abstract

          Biomimetics is the study of nature and natural phenomena to understand the principles of underlying mechanisms, to obtain ideas from nature, and to apply concepts that may benefit science, engineering, and medicine. Examples of biomimetic studies include fluid-drag reduction swimsuits inspired by the structure of shark’s skin, velcro fasteners modeled on burrs, shape of airplanes developed from the look of birds, and stable building structures copied from the backbone of turban shells. In this article, we focus on the current research topics in biomimetics and discuss the potential of biomimetics in science, engineering, and medicine. Our report proposes to become a blueprint for accomplishments that can stem from biomimetics in the next 5 years as well as providing insight into their unseen limitations.

          Most cited references60

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          Microneedles for drug and vaccine delivery.

          Yeu-Chun Kim, Jung-Hwan Park, Mark Prausnitz (2012)
          Microneedles were first conceptualized for drug delivery many decades ago, but only became the subject of significant research starting in the mid-1990's when microfabrication technology enabled their manufacture as (i) solid microneedles for skin pretreatment to increase skin permeability, (ii) microneedles coated with drug that dissolves off in the skin, (iii) polymer microneedles that encapsulate drug and fully dissolve in the skin and (iv) hollow microneedles for drug infusion into the skin. As shown in more than 350 papers now published in the field, microneedles have been used to deliver a broad range of different low molecular weight drugs, biotherapeutics and vaccines, including published human studies with a number of small-molecule and protein drugs and vaccines. Influenza vaccination using a hollow microneedle is in widespread clinical use and a number of solid microneedle products are sold for cosmetic purposes. In addition to applications in the skin, microneedles have also been adapted for delivery of bioactives into the eye and into cells. Successful application of microneedles depends on device function that facilitates microneedle insertion and possible infusion into skin, skin recovery after microneedle removal, and drug stability during manufacturing, storage and delivery, and on patient outcomes, including lack of pain, skin irritation and skin infection, in addition to drug efficacy and safety. Building off a strong technology base and multiple demonstrations of successful drug delivery, microneedles are poised to advance further into clinical practice to enable better pharmaceutical therapies, vaccination and other applications. Copyright © 2012 Elsevier B.V. All rights reserved.
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            Self-healing materials.

            Martin D. Hager, Peter Greil, Christoph Leyens … (2010)
            Self-healing materials are able to partially or completely heal damage inflicted on them, e.g., crack formation; it is anticipated that the original functionality can be restored. This article covers the design and generic principles of self-healing materials through a wide range of different material classes including metals, ceramics, concrete, and polymers. Recent key developments and future challenges in the field of self-healing materials are summarised, and generic, fundamental material-independent principles and mechanism are discussed and evaluated.
            Article 0 comments Cited 257 times – based on 0 reviews     Review now
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              Biomimetics: its practice and theory.

              Julian Vincent, Michael A Pahl, Said Bogatyrev … (2006)
              Biomimetics, a name coined by Otto Schmitt in the 1950s for the transfer of ideas and analogues from biology to technology, has produced some significant and successful devices and concepts in the past 50 years, but is still empirical. We show that TRIZ, the Russian system of problem solving, can be adapted to illuminate and manipulate this process of transfer. Analysis using TRIZ shows that there is only 12% similarity between biology and technology in the principles which solutions to problems illustrate, and while technology solves problems largely by manipulating usage of energy, biology uses information and structure, two factors largely ignored by technology.
              Article 0 comments Cited 148 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (nlm-ta): Int J Nanomedicine
                Journal ID (iso-abbrev): Int J Nanomedicine
                Journal ID (publisher-id): International Journal of Nanomedicine
                Title: International Journal of Nanomedicine
                Publisher: Dove Medical Press
                ISSN (Print): 1176-9114
                ISSN (Electronic): 1178-2013
                Publication date Collection: 2015
                Publication date (Electronic): 08 September 2015
                Volume: 10
                Pages: 5701-5713
                Affiliations
                [1 ]Department of Bionano Technology, Graduate School, Hanyang University, Seoul, Korea
                [2 ]Department of Bionano Engineering, Hanyang University ERICA, Ansan, Korea
                [3 ]Department of Biomedical Engineering, Boston University, Boston, MA, USA
                [4 ]OpenView Venture Partners, Boston, MA, USA
                Author notes
                Correspondence: Jonghoon Choi, 55 Hanyangdae-hak ro, Ansan, 426-791, South Korea, Tel +82 31 400 5203, Fax +82 31 436 8146, Email jonghchoi@ 123456hanyang.ac.kr
                Article
                Publisher ID: ijn-10-5701
                DOI: 10.2147/IJN.S83642
                PMC ID: 4572716
                PubMed ID: 26388692
                SO-VID: 96a56a1c-dc50-4607-ba78-2fb1fc196400
                Copyright © © 2015 Hwang et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License
                License:

                The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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                Subject: Review

                ScienceOpen disciplines: Molecular medicine
                Keywords: biomimicry,tissue engineering,biomaterials,nature,nanotechnology,nanomedicine
                Data availability:
                ScienceOpen disciplines: Molecular medicine
                Keywords: biomimicry, tissue engineering, biomaterials, nature, nanotechnology, nanomedicine

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