11
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Asymmetric chroman synthesis via an intramolecular oxy-Michael addition by bifunctional organocatalysts.

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Cinchona-alkaloid-urea-based bifunctional organocatalysts facilitate the catalytic asymmetric synthesis of chroman derivatives via an intramolecular oxy-Michael addition reaction. Phenol derivatives bearing an easily available (E)-α,β-unsaturated ketone or a thioester moiety are useful substrates for the title transformation. This method represents a facile synthesis of various optically active 2-substituted chromans in high yield.

          Related collections

          Author and article information

          Journal
          Org. Biomol. Chem.
          Organic & biomolecular chemistry
          Royal Society of Chemistry (RSC)
          1477-0539
          1477-0520
          Jan 07 2014
          : 12
          : 1
          Affiliations
          [1 ] Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyotodaigaku-Katsura, Nishikyo, Kyoto 615-8510, Japan. asano.keisuke.5w@kyoto-u.ac.jp matsubara.seijiro.2e@kyoto-u.ac.jp.
          Article
          10.1039/c3ob41938j
          24201562
          971ead58-e8e9-49a0-a3a9-01dd8102eef1
          History

          Comments

          Comment on this article