This paper is a study of power series, where the coefficients are binomial expressions (iterated finite differences). Our results can be used for series summation, for series transformation, or for asymptotic expansions involving Stirling numbers of the second kind. In certain cases we obtain asymptotic expansions involving Bernoulli polynomials, poly-Bernoulli polynomials, or Euler polynomials. We also discuss connections to Euler series transformations and other series transformation formulas.