Graphene and graphene oxide: biofunctionalization and applications in biotechnology

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Graphene is the basic building block of 0D fullerene, 1D carbon nanotubes, and 3D graphite. Graphene has a unique planar structure, as well as novel electronic properties, which have attracted great interests from scientists. This review selectively analyzes current advances in the field of graphene bioapplications. In particular, the biofunctionalization of graphene for biological applications, fluorescence-resonance-energy-transfer-based biosensor development by using graphene or graphene-based nanomaterials, and the investigation of graphene or graphene-based nanomaterials for living cell studies are summarized in more detail. Future perspectives and possible challenges in this rapidly developing area are also discussed.

Related collections

Most cited references 41

Record: found
Abstract: not found
Article: not found

Honeycomb carbon: a review of graphene.

Matthew J Allen, Vincent Tung, Richard B Kaner (2010)

0 comments Cited 1345 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

PEGylated nanographene oxide for delivery of water-insoluble cancer drugs.

Zhuang Liu, Joshua T Robinson, Xiaoming Sun … (2008)

It is known that many potent, often aromatic drugs are water insoluble, which has hampered their use for disease treatment. In this work, we functionalized nanographene oxide (NGO), a novel graphitic material, with branched polyethylene glycol (PEG) to obtain a biocompatible NGO-PEG conjugate stable in various biological solutions, and used them for attaching hydrophobic aromatic molecules including a camptothecin (CPT) analogue, SN38, noncovalently via pi-pi stacking. The resulting NGO-PEG-SN38 complex exhibited excellent water solubility while maintaining its high cancer cell killing potency similar to that of the free SN38 molecules in organic solvents. The efficacy of NGO-PEG-SN38 was far higher than that of irinotecan (CPT-11), a FDA-approved water soluble SN38 prodrug used for the treatment of colon cancer. Our results showed that graphene is a novel class of material promising for biological applications including future in vivo cancer treatment with various aromatic, low-solubility drugs.

0 comments Cited 803 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

P25-graphene composite as a high performance photocatalyst.

Hao Zhang, Xiaojun Lv, Yueming Li … (2010)

Herein we obtained a chemically bonded TiO(2) (P25)-graphene nanocomposite photocatalyst with graphene oxide and P25, using a facile one-step hydrothermal method. During the hydrothermal reaction, both of the reduction of graphene oxide and loading of P25 were achieved. The as-prepared P25-graphene photocatalyst possessed great adsorptivity of dyes, extended light absorption range, and efficient charge separation properties simultaneously, which was rarely reported in other TiO(2)-carbon photocatalysts. Hence, in the photodegradation of methylene blue, a significant enhancement in the reaction rate was observed with P25-graphene, compared to the bare P25 and P25-CNTs with the same carbon content. Overall, this work could provide new insights into the fabrication of a TiO(2)-carbon composite as high performance photocatalysts and facilitate their application in the environmental protection issues.

0 comments Cited 623 times – based on 0 reviews      Review now

Bookmark

All references

Author and article information

Contributors

Jinghong Li

Yuehe Lin

Journal

Journal ID (nlm-ta): Trends Biotechnol

Journal ID (iso-abbrev): Trends Biotechnol

Title: Trends in Biotechnology

Publisher: Elsevier Ltd.

ISSN (Print): 0167-7799

ISSN (Electronic): 1879-3096

Publication date PMC-release: 10 March 2011

Publication date (Print): May 2011

Publication date (Electronic): 10 March 2011

Volume: 29

Issue: 5

Pages: 205-212

Affiliations

[1 ]Department of Chemistry, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing 100084, People's Republic of China

[2 ]Pacific Northwest National Laboratory, Richland, WA 99352, USA

Article

Publisher ID: S0167-7799(11)00019-9

DOI: 10.1016/j.tibtech.2011.01.008

PMC ID: 7114214

PubMed ID: 21397350

SO-VID: 976f25f6-92d6-410e-b04a-1888b4579158

License:

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.