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      Functional decline in nursing home residents: A prognostic study

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          Abstract

          Aim

          To verify the probability of maintaining functional capacity in basic activities of daily living and identify the prognostic factors of functional decline in institutionalized older adults.

          Methods

          A longitudinal study is presented herein, with 5 waves every 6 months, throughout 2 years (2013–2015), conducted with individuals ≥60 years old in 10 nursing homes in the city of Natal-RN (Brazil). Functional capacity was assessed by the items ‘eating’, ‘personal hygiene’, ‘dressing’, ‘bathing’, ‘transferring’, ‘toileting’ and ‘walking’, through a 5-item Likert scale. Sociodemographic, institution-related and health-related variables were considered to establish the baseline. Time dependent variables included continence decline, cognitive decline, increase in the number of medication, and incidences of falls, hospitalizations and fractures. The actuarial method, the log-rank test and Cox's regression were applied as statistical methods.

          Results

          The cumulative probability of functional maintenance was 78.2% (CI 95%: 72.8–82.7%), 65.1% (CI 95%: 58.9–70.5%), 53.5% (CI 95%: 47.2–59.5%) and 44.0% (CI 95%: 37.7–50.2%) at 6, 12, 18 and 24 months, respectively. Predicting factors for functional decline were: severe cognitive impairment (HR = 1.96; p = 0.001), continence decline (HR = 1.85; p = 0.002) and incidence of hospitalizations (HR = 1.62; p = 0.020), adjusted by the incidence of depression, age, education level, presence of chronic diseases and low weight.

          Conclusions

          The cumulative probability of maintaining functional capacity in institutionalized older adults was only 44% at the 2-year follow-up. Prognostic factors for functional decline included severe cognitive impairment, continence decline and incidence of hospitalizations.

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          Most cited references21

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          Screening for nutritional status in the elderly.

          A comprehensive assessment of nutritional status is a critically important component of any patient evaluation. Based upon clinical information, anthropometric data, and a small number of laboratory investigations, an accurate appraisal of nutritional status should be possible and an appropriate intervention plan can be developed. The actual approach depends on the particular problem discovered. These are discussed in detail elsewhere in this issue.
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            Risk factors for functional status decline in community-living elderly people: a systematic literature review.

            To lay the groundwork for devising, improving and implementing strategies to prevent or delay the onset of disability in the elderly, we conducted a systematic literature review of longitudinal studies published between 1985 and 1997 that reported statistical associations between individual base-line risk factors and subsequent functional status in community-living older persons. Functional status decline was defined as disability or physical function limitation. We used MEDLINE, PSYCINFO, SOCA, EMBASE, bibliographies and expert consultation to select the articles, 78 of which met the selection criteria. Risk factors were categorized into 14 domains and coded by two independent abstractors. Based on the methodological quality of the statistical analyses between risk factors and functional outcomes (e.g. control for base-line functional status, control for confounding, attrition rate), the strength of evidence was derived for each risk factor. The association of functional decline with medical findings was also analyzed. The highest strength of evidence for an increased risk in functional status decline was found for (alphabetical order) cognitive impairment, depression, disease burden (comorbidity), increased and decreased body mass index, lower extremity functional limitation, low frequency of social contacts, low level of physical activity, no alcohol use compared to moderate use, poor self-perceived health, smoking and vision impairment. The review revealed that some risk factors (e.g. nutrition, physical environment) have been neglected in past research. This review will help investigators set priorities for future research of the Disablement Process, plan health and social services for elderly persons and develop more cost-effective programs for preventing disability among them.
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              Validation of the National Institutes of Health Stroke Scale, Modified Rankin Scale and Barthel Index in Brazil: The Role of Cultural Adaptation and Structured Interviewing

              Background: We aimed to validate three widely used scales in stroke research in a multiethnic Brazilian population. Methods: The National Institutes of Health Stroke Scale (NIHSS), modified Rankin Scale (mRS) and Barthel Index (BI) were translated, culturally adapted and applied by two independent investigators. The mRS was applied with or without a previously validated structured interview. Interobserver agreement (kappa statistics) and intraclass correlation coefficients were calculated. Results: 84 patients underwent mRS (56 with and 28 without a structured interview), 57 BI and 62 NIHSS scoring. Intraclass correlation coefficient was 0.902 for NIHSS and 0.967 for BI. For BI, interobserver agreement was good (kappa = 0.70). For mRS, the structured interview improved interobserver agreement (kappa = 0.34 without a structured interview; 0.75 with a structured interview). Conclusion: The NIHSS, BI and mRS show good validity when translated and culturally adapted. Using a structured interview for the mRS improves interobserver concordance rates.
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                Author and article information

                Contributors
                Role: Editor
                Journal
                PLoS One
                PLoS ONE
                plos
                plosone
                PLoS ONE
                Public Library of Science (San Francisco, CA USA )
                1932-6203
                11 May 2017
                2017
                : 12
                : 5
                : e0177353
                Affiliations
                [1 ]Postgraduate Program in Collective Health, Odontology Department, Federal University of Rio Grande do Norte (UFRN), Avenida Salgado Filho 1787, Lagoa Nova, Natal-RN, Brazil
                [2 ]Can Misses Hospital, Ibiza, Spain
                [3 ]Postgraduate Program in Health Sciences, Center of Health Sciences, Federal University of Rio Grande do Norte (UFRN), Av. Gustavo Cordeiro de Farias, s/n, Petrópolis, Natal RN, Natal-RN, Brazil
                Banner Alzheimer's Institute, UNITED STATES
                Author notes

                Competing Interests: The authors have declared that no competing interests exist.

                • Conceptualization: JJ KCL.

                • Data curation: JJ LMBMF JRTA.

                • Formal analysis: JJ.

                • Investigation: JJ LMBMF JRTA.

                • Methodology: JJ LMBMF KCL.

                • Project administration: JJ LMBMF KCL.

                • Resources: JJ LMBMF JRTA.

                • Software: JJ.

                • Supervision: JJ LMBMF JRTA KCL.

                • Validation: JJ LMBMF JRTA.

                • Visualization: JJ LMBMF.

                • Writing – original draft: JJ LMBMF JRTA KCL.

                • Writing – review & editing: JJ LMBMF JRTA KCL.

                Article
                PONE-D-16-47275
                10.1371/journal.pone.0177353
                5426763
                28493946
                97979d9a-a1cc-4ba2-afe4-67eebba9a04d
                © 2017 Jerez-Roig et al

                This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 29 November 2016
                : 26 April 2017
                Page count
                Figures: 1, Tables: 5, Pages: 14
                Funding
                The authors received no specific funding for this work.
                Categories
                Research Article
                Biology and Life Sciences
                Neuroscience
                Cognitive Science
                Cognitive Neuroscience
                Cognitive Neurology
                Cognitive Impairment
                Biology and Life Sciences
                Neuroscience
                Cognitive Neuroscience
                Cognitive Neurology
                Cognitive Impairment
                Medicine and Health Sciences
                Neurology
                Cognitive Neurology
                Cognitive Impairment
                People and Places
                Population Groupings
                Age Groups
                Elderly
                Medicine and Health Sciences
                Urology
                Incontinence
                Research and Analysis Methods
                Research Design
                Longitudinal Studies
                Social Sciences
                Sociology
                Education
                Educational Attainment
                Computer and Information Sciences
                Data Visualization
                Infographics
                Charts
                Medicine and Health Sciences
                Nephrology
                Medicine and Health Sciences
                Urology
                Custom metadata
                Data are available from the “Envelhecimento humano e saúde – a realidade dos idosos institucionalizados da cidade do Natal/RN” study for researchers who meet the criteria for access confidential data. Data requests should be sent to the Postgraduate Program in Collective Health ppgscol@ 123456dod.ufrn.br .

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                Uncategorized

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