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      Massage treatment of chronic persistent pediatric asthma

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          Abstract

          Objective: We observed the clinical effect of massage in treating chronic persistent pediatric asthma and the changes in expression of TLR1, TLR2, and TLR4 on macrophages.

          Methods: One hundred sixty pediatric patients with persistent chronic asthma were collected, and divided into treatment and control groups of 80 each in strict accordance with the principle of random allocation. The patients in the control group received general nebulizer therapy, and the patients in the treatment group received infantile massage. Both groups of patients were observed for 3 months with respect to the following indicators: the frequency of asthmatic attacks; the frequency of respiratory tract infections (RTIs); C-ACT rating; and the PEF% of peripheral blood (PB) before and after treatment to detect macrophage TLR1, TLR2, and TLR4.

          Results: After treatment, the frequency of asthmatic attacks, frequency of RTIs, C-ACT rating, and the PEF% and macrophage TLR1, TLR2, and TLR4 expression of fluorescence intensity in the treatment group showed a statistically significant increase when compared with the control group ( P<0.05).

          Conclusion: Pediatric massage can improve the clinical symptoms of pediatric asthma by up-regulating the expression of macrophage TLR1, TLR2, and TLR4.

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          Most cited references 19

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          Mast cells and inflammation

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            Mast cells in allergy: innate instructor of adaptive responses

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              Observation of curative effect of feet hole for treatment of pediatric asthma in the stage of non-attack

               O. Chen,  YI Li,  J Zhong (2013)
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                Author and article information

                Journal
                FMCH
                Family Medicine and Community Health
                FMCH
                Family Medicine and Community Health & American Chinese Medical Education Association (USA )
                xxx-xxx
                2305-6983
                June 2014
                December 2014
                : 2
                : 2
                : 10-14
                Affiliations
                1College of Traditional Chinese Medicine, Hebei United University, Hebei 063000, China
                Author notes
                CORRESPONDING AUTHOR: Qi Li, College of Traditional Chinese Medicine, Hebei United University, Hebei 063000, China, E-mail: liqi19801211@ 123456163.com
                Article
                fmch20140122
                10.15212/FMCH.2014.0122
                Copyright © 2014 Family Medicine and Community Health

                This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License (CC BY-NC 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc/4.0/.

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                Self URI (journal page): http://fmch-journal.org/
                Categories
                Original Research

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