10
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Triterpenoid saponins from Clematis tangutica and their cardioprotective activities.

      Fitoterapia
      Animals, Anoxia, Cells, Cultured, Clematis, chemistry, Molecular Structure, Myocytes, Cardiac, drug effects, Oxygen Consumption, Saponins, pharmacology, Triterpenes

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Phytochemical investigation of the whole plants of Clematis tangutica led to the isolation of three new triterpenoid saponins (1-3), together with four known saponins (4-7). Their structures were determined by extensive spectral analysis and chemical evidences. Compounds 1-7 were evaluated for their cardioprotective activities in cardiomyocytes anoxia/reoxygenation (A/R) model. The results showed that those saponins exhibited cardioprotective effects by decreasing the levels of creatine kinase-MB (CK-MB) and lactate dehydrogenase (LDH). Copyright © 2012 Elsevier B.V. All rights reserved.

          Related collections

          Author and article information

          Journal
          23266737
          10.1016/j.fitote.2012.12.011

          Chemistry
          Animals,Anoxia,Cells, Cultured,Clematis,chemistry,Molecular Structure,Myocytes, Cardiac,drug effects,Oxygen Consumption,Saponins,pharmacology,Triterpenes

          Comments

          Comment on this article