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      Infliximab for the treatment of fistulas in patients with Crohn's disease.

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      Journal: The New England journal of medicine
      Publisher: Massachusetts Medical Society

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          Abstract

          Enterocutaneous fistulas are a serious complication of Crohn's disease and are difficult to treat. Infliximab, a chimeric monoclonal antibody to tumor necrosis factor alpha, has recently been developed as a treatment for Crohn's disease. We conducted a randomized, multicenter, double-blind, placebo-controlled trial of infliximab for the treatment of fistulas in patients with Crohn's disease.

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          PubMed ID:: 10228190
          DOI:: 10.1056/NEJM199905063401804

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