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      Topographic Pattern of Advanced Atherosclerotic Lesions in Carotid Arteries

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          Abstract

          Ulcers in extracranial carotid arteries are a known source of cerebral embolism. However, there are no data available on the prevalence of ulcerations located at the origin of these vessels in the aortic arch. Therefore, in this pathological study the topographic distribution of ulcerated lesions were determined in these arteries. One hundred and one consecutively autopsied patients composed the study group. Ulcerated plaques were sought for in both carotid arteries, from their origin in the arch up to the carotid canal, and also in the aortic arch and ascending aorta. The two anatomical sites mostly affected by atherosclerosis were the region of the carotid sinus and the orifices of cervical arteries in the aortic arch. More than one third of all ulcers were at the orifices of cervical arteries in the arch. Interestingly, ulcers at the orifice of the left common carotid artery in the arch were accompanied with other ulcers located elsewhere in the remaining segments of the left carotid system, whereas ulcerations at the orifice of brachiocephalic trunk were not accompanied with other concomitant lesions in the right carotid system. Furthermore, there was no symmetric distribution of ulcerated plaques in both carotid systems.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1998
          March 1998
          16 March 1998
          : 89
          : 3
          : 235-240
          Affiliations
          Departments of a Cardiology and b Pathology, Medical University of Lübeck, Germany
          Article
          6793 Cardiology 1998;89:235–240
          10.1159/000006793
          9570440
          © 1998 S. Karger AG, Basel

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          Page count
          Figures: 1, Tables: 1, References: 45, Pages: 6
          Categories
          Cardiovascular Pathology

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