Metástasis en la mama de carcinoma renal

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Abstract

Las metástasis en la mama de neoplasias sólidas extramamarias son inusuales. Deben ser claramente diferenciadas del carcinoma primario de la glándula debido a su diferente pronóstico y tratamiento. La metástasis en la mama de un carcinoma renal es aún más rara. Se describe aquí el caso de una mujer de 57 años con una metástasis en la mama de un carcinoma renal de células claras, previamente tratado.

Translated abstract

Metástasis to the breast from extramammary solid neoplasms is a very unusual condition. It must be clearly distinguished from primary carcinoma of the gland because of its different treatment and prognosis. Metastasis from renal carcinoma to the breast is even more rare. We herein report a case of a 57 years old woman, with a metastasis to the breast of a previously treated clear cell renal carcinoma.

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Metastatic disease to the breast: the Washington University experience

Aislinn Vaughan, Jill R Dietz, Jeffrey F Moley … (2007)

Background Metastases to the breast occur rarely, but may be increasing in incidence as patients live longer with malignant diseases. The aim of this study is to characterize metastatic disease to the breast and to describe the management and prognosis of patients who present with this diagnosis. Methods A retrospective review of our institution's pathology and breast cancer databases was performed in order to identify patients with breast malignancies that were not of primary breast origin. Chart review provided additional information about the patients' primary malignancies and course of illness. Results Between 1991 and 2006, eighteen patients with metastatic disease to the breast of non-hematologic origin were identified and all had charts available for review. Among the 18 patients with disease metastatic to the breast, tissues of origin included 3 ovarian, 6 melanoma, 3 medullary thyroid, 3 pulmonary neuroendocrine, 1 pulmonary small cell, 1 oral squamous cell, and 1 renal cell. Overall mean survival after diagnosis of metastatic disease to the breast was 22.4 months. Treatment of metastases varied and included combinations of observation, surgery, radiation, and chemotherapy. Five patients (27.8%) required a change in management of their breast disease for local control. Conclusion Due to the variable course of patients with metastatic disease, a multi-disciplinary approach is necessary for each patient with disease metastatic to the breast to determine optimal treatment. Based on our review, many patients survive for long periods of time and local treatment of metastases to the breast may be beneficial in these patients to prevent local complications.

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Breast metastasis from a renal cell cancer

Ahmed Alzaraa, Aleksandar Vodovnik, Hugh Montgomery … (2007)

Background Metastases to the breast from extramammary tumours are uncommon, and metastatic renal cell carcinoma to the breast is extremely rare. We report a metastasis to the breast from a renal primary with the radiological and histopathological features. Case presentation An 81-year-old lady was seen in the breast clinic for a right breast mass after sustaining a fall. Clinical examination and investigations revealed a metastatic cancer from a renal primary. She received surgical treatment only and is under regular follow-up in the oncology clinic. Conclusion The treatment strategy for metastatic breast diseases is based on a proper assessment of such cases by surgeons, radiologists and histopathologists.