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      Ethylene Glycol Poisoning in the Czech Republic (2000–2002)

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          Background: The objective of the study was to evaluate the severity of kidney damage retrospectively and to analyze prognostic factors following ethylene glycol (EG) poisonings. Methods: Data concerning the clinical course of patients with EG poisoning between 2000 and 2002 were analyzed. The χ<sup>2</sup> test, Student’s t test, Fisher’s test and the calculation of linear correlation coefficients were used for statistical analysis. Results: Thirty-three discharge records were obtained. Three patients died, and 11 patients developed acute renal failure (mean maximum serum creatinine level 618 µmol/l). Upon discharge, serum creatinine levels were still elevated in 10 patients. In all but 1 patient, renal function completely normalized within 20 months after intoxication. Conclusion: Adult men are the most endangered segment of the population. The most important prognostic factors are the ingested dose and early antidotal treatment. EG toxic kidney damage is reversible.

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          Most cited references 9

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          2003 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System.

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            Ethylene glycol poisoning.

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              Consequences of ethylene glycol poisoning


                Author and article information

                Blood Purif
                Blood Purification
                S. Karger AG
                February 2006
                15 February 2006
                : 24
                : 2
                : 180-184
                aToxicological Information Centre, Department of Occupational Medicine, 1st Faculty of Medicine, Charles University and General Teaching Hospital, bJ. Heyrovský Institute of Physical Chemistry, and c1st Medical Department, Clinical Department of Hematology and Nephrology, 1st Faculty of Medicine, Charles University and General Teaching Hospital, Prague, Czech Republic
                90516 Blood Purif 2006;24:180–184
                © 2006 S. Karger AG, Basel

                Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

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                Tables: 3, References: 18, Pages: 5
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