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      Noninvasive Assessment of Systolic and Diastolic Function in 50 Patients with Friedreich’s Ataxia

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          Abstract

          Fifty consecutive patients with Friedreich’s ataxia were examined to characterize their cardiac diastolic function. Electrocardiographic abnormalities were detected in 42 (80%) of the 50 patients. Echocardiography showed left ventricular hypertrophy in 14 patients (28%): concentric in 12 and asymmetric in 2. Left ventricular percent fractional shortening was normal in all except 2 patients. Diastolic filling characteristics measured from Doppler mitral flow velocity traces were not statistically different from those of 18 healthy control subjects. No abnormal diastolic flow pattern was observed in patients with left ventricular hypertrophy, whether concentric or asymmetric.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1988
          1988
          11 November 2008
          : 75
          : 5
          : 321-327
          Affiliations
          Departments of aInternal Medicine and bNeurology, 2nd School of Medicine, University of Naples, Italy
          Article
          174394 Cardiology 1988;75:321–327
          10.1159/000174394
          3233613
          © 1988 S. Karger AG, Basel

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          Page count
          Pages: 7
          Categories
          Original Paper

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