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      Endobronchial lipomatous hamartoma diagnosed on computed tomography scan in young new mother—A case report

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          Abstract

          INTRODUCTION

          Hamartoma is the most common benign lesion of the lung, but endobronchial localisation is rare. Typically occurs between the fifth and seventh decade of life and in literature has never been described in association with pregnancy.

          PRESENTATION OF CASE

          We report the case of a young woman in whom the tumor seems to have an increase of size after two pregnancies in the course of his life.

          DISCUSSION

          The pulmonary hamartoma is the most common benign lesion of the lung, but endobronchial localisation is rare. Early diagnosis and resection of benign endobronchial tumors may avert significant morbidity and prevent distal lung damage.

          CONCLUSION

          Following histological examination reassessment of the clinical history of our patient led us to hypothesize, on the basis of pathophysiological, a rise in the size of the endobronchial lesion given by hormonal stimulation pregnancy-related.

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          Most cited references7

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          Fat-containing lesions of the chest.

          Although most lesions that occur in the chest have a nonspecific soft-tissue appearance, fat-containing lesions are occasionally encountered at cross-sectional computed tomography (CT) or magnetic resonance imaging. The various fat-containing lesions of the chest include parenchymal and endobronchial lesions such as hamartoma, lipoid pneumonia, and lipoma. Endobronchial hamartoma usually appears at CT as a lesion with a smooth edge, focal collections of fat, or fat collections that alternate with foci of calcification. Mediastinal fat-containing lesions include germ cell neoplasms, thymolipomas, lipomas, and liposarcomas. The most frequent CT manifestation of the germ cell neoplasm teratoma is a heterogeneous mass with soft-tissue, fluid, fat, and calcium attenuation. Cardiac lesions with fat content include lipomatous hypertrophy of the interatrial septum and arrhythmogenic right ventricular dysplasia. Diagnosis of the former is made with CT when a smooth, nonenhancing, well-marginated fat-containing lesion is identified in the interatrial septum. Finally, fat may herniate into the chest at several characteristic locations. When such a lesion is identified, the time required for differential diagnosis is significantly reduced, often allowing a definitive radiologic diagnosis. Sagittal and coronal reformatted images can add valuable information by showing diaphragmatic defects and hernia contents.
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            Endobronchial lipomatous hamartoma: an unusual cause of bronchial obstruction (2007: 7b).

            Imaging findings were reported in an unusual case of endobronchial lipomatous hamartoma obstructing the left mainstem bronchus. Computed tomography readily demonstrated the presence of fat density within the lesion narrowing the differential diagnosis to endobronchial lipoma or lipomatous hamartoma.
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              The prevalence and age distribution of peripheral pulmonary hamartomas in adult males. An autopsy-based study.

              This autopsy-based study defined the prevalence and age distribution of peripheral pulmonary hamartomas in 47,635 southern African miners examined between 1975 and 1988. The prevalence rate for white miners was 7.5/1,000 and for black miners 1.1/1,000. When directly standardised to the white men in the general population, the rates for white and black miners were 7.2 and 5.5/1,000, respectively. The prevalence of peripheral pulmonary hamartomas in both groups increased with age, from 0.8/1,000 in the third decade to 12.0/1,000 in the eighth decade. The study showed a much higher prevalence of peripheral pulmonary hamartomas for whites than previously reported. Furthermore, it documented the occurrence of these benign lung tumours in blacks, a fact that has previously been questioned. There appeared to be no significant difference in prevalence and age distribution between white and black miners, although the database for the black group was deficient for the later decades of life.
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                Author and article information

                Contributors
                Journal
                Int J Surg Case Rep
                Int J Surg Case Rep
                International Journal of Surgery Case Reports
                Elsevier
                2210-2612
                05 November 2014
                05 November 2014
                2014
                : 5
                : 12
                : 1113-1116
                Affiliations
                [0005]Azienda Ospedaliera-Universitaria di Ferrara, Struttura Complessa di Radiologia Universitaria – Dipartimento di Diagnostica per Immagini e Medicina di Laboratorio, via Aldo Moro, 8, 44124 Ferrara, Italy
                Author notes
                [* ]Corresponding author. Tel.: +39 3202629633. defalco.md@ 123456gmail.com
                Article
                S2210-2612(14)00226-0
                10.1016/j.ijscr.2014.09.017
                4276084
                25437651
                993220d8-3594-47ef-ab95-0650971c0844
                © 2014 The Authors

                This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).

                History
                : 13 January 2014
                : 3 September 2014
                : 11 September 2014
                Categories
                Article

                endobronchial lipomatous hamartoma,ct scan,pregnancy,young new mother

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