Hiroaki Kitamura: Role: Data curationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
Writing – original draft
Yoko Tabe:
ORCID: http://orcid.org/0000-0002-3734-0346
Role: ConceptualizationRole: Formal analysisRole: Project administrationRole: SupervisionRole:
Writing – review & editing
Tomohiko Ai: Role: Formal analysisRole: Writing – original draft
Koji Tsuchiya: Role: Data curationRole: Formal analysis
Maiko Yuri: Role: Data curationRole: Formal analysisRole: Methodology
Shigeki Misawa: Role: Formal analysisRole: Supervision
Takashi Horii: Role: Supervision
Atsushi Kawaguchi: Role: Data curationRole: Formal analysis
Akimichi Ohsaka: Role: Formal analysisRole: MethodologyRole: Supervision
Shinya Kimura: Role: ConceptualizationRole: Formal analysisRole: InvestigationRole: Project administrationRole:
SupervisionRole: Writing – review & editing
Xiaoyan Jiang: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
5
March
2019
Publication date Collection: 2019
Volume: 14
Issue: 3
Electronic Location Identifier: e0207170
Affiliations
[1
]
Division of Hematology, Respiratory Medicine and Oncology, Department of Internal
Medicine, Faculty of Medicine, Saga University, Saga, Japan
[2
]
Department of Next Generation Hematology Laboratory Medicine, Juntendo University
Graduate School of Medicine, Bunkyo-ku, Tokyo, Japan
[3
]
Department of Clinical Laboratory Medicine, Juntendo University Graduate School of
Medicine, Bunkyo-ku, Tokyo, Japan
[4
]
Department of Clinical Laboratory, Juntendo University Hospital, Bunkyo-ku, Tokyo,
Japan
[5
]
Education and Research Center for Community Medicine, Faculty of Medicine, Saga University,
Saga, Japan
University of British Columbia, CANADA
Author notes
Competing Interests: The department of Next Generation Hematology Laboratory Medicine, Juntendo University
School of Medicine has been endowed by Sysmex (Kobe, Japan). Y.T. has served as an
endowed chair. S.K. has received honorariums from Bristol-Myers Squibb, Novartis,
Pfizer, Otsuka Pharmaceutical, and OHARA Pharmaceutical for his lectures, outside
the submitted work. This does not alter our adherence to PLOS ONE policies on sharing
data and materials.
Author information
Article
Publisher ID:
PONE-D-18-30679
DOI: 10.1371/journal.pone.0207170
PMC ID: 6400442
PubMed ID: 30835732
SO-VID: 99879de8-c418-46ff-a486-2f5fa54319c0
Copyright © © 2019 Kitamura et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
The department of Next Generation Hematology Laboratory Medicine, Juntendo University
School of Medicine has been endowed by Sysmex (Kobe, Japan). Y.T. has received a research
endowment including partial salary support (Y.T.) from Sysmex. The funders had no
role in study design, data collection and analysis, decision to publish, or preparation
of the manuscript.
Subject:
Research Article
Subject:
Biology and life sciences
Subject:
Molecular biology
Subject:
Molecular biology techniques
Subject:
Sequencing techniques
Subject:
RNA sequencing
Subject:
Research and analysis methods
Subject:
Molecular biology techniques
Subject:
Sequencing techniques
Subject:
RNA sequencing
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Nucleic acids
Subject:
RNA
Subject:
Messenger RNA
Subject:
Medicine and Health Sciences
Subject:
Clinical Medicine
Subject:
Clinical Trials
Subject:
Medicine and Health Sciences
Subject:
Pharmacology
Subject:
Drug Research and Development
Subject:
Clinical Trials
Subject:
Research and Analysis Methods
Subject:
Clinical Trials
Subject:
Medicine and Health Sciences
Subject:
Public and Occupational Health
Subject:
Global Health
Subject:
Research and analysis methods
Subject:
Extraction techniques
Subject:
RNA extraction
Subject:
Research and analysis methods
Subject:
Chemical synthesis
Subject:
Biosynthetic techniques
Subject:
Nucleic acid synthesis
Subject:
RNA synthesis
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Nucleic acids
Subject:
RNA
Subject:
RNA synthesis
Subject:
Medicine and Health Sciences
Subject:
Oncology
Subject:
Cancers and Neoplasms
Subject:
Hematologic Cancers and Related Disorders
Subject:
Leukemias
Subject:
Myeloid Leukemia
Subject:
Chronic Myeloid Leukemia
Subject:
Medicine and Health Sciences
Subject:
Hematology
Subject:
Hematologic Cancers and Related Disorders
Subject:
Leukemias
Subject:
Myeloid Leukemia
Subject:
Chronic Myeloid Leukemia
Subject:
Medicine and Health Sciences
Subject:
Oncology
Subject:
Cancers and Neoplasms
Subject:
Hematologic Cancers and Related Disorders
Subject:
Myeloproliferative Disorders
Subject:
Chronic Myeloid Leukemia
Subject:
Medicine and Health Sciences
Subject:
Hematology
Subject:
Hematologic Cancers and Related Disorders
Subject:
Myeloproliferative Disorders
Subject:
Chronic Myeloid Leukemia
Subject:
People and Places
Subject:
Geographical Locations
Subject:
Asia
Subject:
Japan