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      Naltrexone Suppresses Abnormal Sexual Behavior in Tourette's Syndrome

      International Journal of Neuroscience

      Informa UK Limited

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          Most cited references 16

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          Opioids and sexual behavior

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            β-Endorphin and male sexual behavior

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              Gilles de la Tourette syndrome: clinical and family study of 50 cases.

               L Nee,  E Caine,  R Polinsky (1980)
              Fifty patients with Tourette syndrome were evaluated; data included family history, clinical characteristics, response to haloperidol, and side effects during haloperidol therapy. Sixteen patients had a family history of Tourette syndrome, and another 16 had a family history of tics. Twenty-four families had more than 2 members with Tourette syndrome or tics. There was no preponderance of families with a Jewish, Eastern European background in this sample. Thirty-four patients had obsessive-compulsive behavior. Among the 50 patients there was a high frequency of sleep disturbance, learning disability, self-destructive behavior, inappropriate sexual activity, and antisocial behavior. Family history was significantly related to the occurrence of sleep disturbance, obsessive-compulsive behavior, haloperidol response, and the frequency of side effects caused by haloperidol. The precise mode of genetic transmission in familial Tourette syndrome remains to be determined.
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                Author and article information

                Journal
                International Journal of Neuroscience
                International Journal of Neuroscience
                Informa UK Limited
                0020-7454
                1543-5245
                July 07 2009
                January 1988
                July 07 2009
                January 1988
                : 43
                : 1-2
                : 107-110
                Article
                10.3109/00207458808985786
                © 1988

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