First of all, I would like to extend our sincere condolences to the people who suffered
from the Great Tohoku-Kanto Earthquake and Tsunami.
In the aftermath of the damage caused by the earthquake and tsunami, the Board of
Directors of the Japan Epidemiological Association (JEA) conducted the following activities
to provide our colleagues and fellow citizens with useful information that will assist
them in coping with the disaster and accurately assessing the health effects of radiation
exposure:
(1)
Tips and guidelines for coping with the effects of the earthquake and tsunami, as
well as information from relevant websites, were posted on our website and sent to
our members by email.
(2)
On March 25, the Board of Directors made a public announcement on our website entitled
“Possible health effects of the Fukushima nuclear accident”, which explained the health
effects of radiation exposure, based on information contained in the reports of UNSCEAR
(United Nation Scientific Committee on the Effects of Atomic Radiation), and presented
our understanding of the situation.
(3)
Questions and Answers—a revision of the explanation in our initial announcement, with
additional explanatory information, was posted on our website on 13 April.
The direct and indirect effects of the quake and tsunami are enormous, and our society
has been seriously affected by this disaster. It will be remembered as a turning point
in the history of Japan. For the JEA, it is important to develop and conduct activities
that address the consequent health and social problems. As our first academic activity,
we plan to hold a symposium related to these concerns at the 22nd Annual Meeting of
the JEA, which is being organized by Professor Naohito Yamaguchi. The themes and topics
to be addressed are now being discussed by the Academic Activities Committee.
The Japanese government is now making plans to initiate periodical health check-ups
and long-term follow-up of residents in Iwate, Miyagi, and Fukushima, the prefectures
most affected by the quake and tsunami. There are also plans for similar programs
and epidemiological studies of residents evacuated from designated areas and workers
who have been mobilized to cope with the nuclear accidents. A number of JEA members
are expected to participate in these endeavors, and the JEA will discuss how to provide
necessary support for those efforts.
Last, but not least, we offer our thanks for the condolences and support extended
by our foreign colleagues.
POSSIBLE HEALTH EFFECTS OF THE FUKUSHIMA NUCLEAR ACCIDENT
March 25, 2011
Board of Directors
Japan Epidemiological Association
First, we would like to extend our sincere condolences to all who suffered in the
Great Tohoku-Kanto Earthquake and Tsunami. As reported by the media, the Japanese
government has declared Nuclear Emergency Situations at Fukushima Dai-ichi Nuclear
Power Plant (Fukushima I NPP) and Fukushima Dai-ni Nuclear Power Plant (Fukushima
II NPP) in accordance with the Act on Special Measures Concerning Nuclear Emergency
Preparedness. The spread of radioactive nuclides near the damaged power plants is
of great concern. To minimize radiation exposure, residents in a 20-kilometer radius
have been instructed to evacuate and those inside a 30-kilometer zone have been advised
to remain indoors.
As specialists in epidemiology—an important auxiliary branch of medicine that, among
other activities, evaluates the health effects of radiation—we would like to briefly
describe the effects of ionizing radiation on human health, based on information contained
in the reports of the United Nations Scientific Committee on Atomic Radiation (UNSCEAR),
and offer our interpretation. Additional relevant information and links to useful
websites are included on the website of the Japan Epidemiological Association (JEA).
1. Environmental radiation levels
In this nuclear accident, radioactive nuclides, including iodine-131 (I-131) and Cesium-137
(Cs-137) from the nuclear reactors, were released into the air and spread over wide
areas around the plant. The radiation dose decreases rapidly as the distance from
the power plant increases. The dose is also affected by wind direction, topography,
and the amount of precipitation. Therefore, environmental radiation levels are affected
by these factors.
Monitoring data from the Ministry of Education, Science and Technology (MEXT; http://www.mext.go.jp/)
indicate that in some areas radiation levels reached several hundred microsieverts
per hour (µSv/hr, a common measure of radiation exposure). However, these high radiation
levels lasted only for a short period, and the average doses were low.
Radionuclides, including I-131, were found outside of Fukushima Prefecture, and contamination
of water, some vegetables, and milk were reported. In addition, a survey by MEXT showed
extremely high levels of Cs-137 in soil collected in Fukushima Prefecture, raising
concerns about contamination of vegetables. On March 23, I-131 was found in the tap
water of the Tokyo metropolitan area and Ibaragi Prefecture, in addition to Fukushima
Prefecture. On the basis of these findings, the media recommended refraining from
drinking tap water.
The website of the Ministry of Health, Labor and Welfare (MHLW) presents a notice
entitled “Measures for tap water if radiation levels exceed safety limits due to the
nuclear power plant accident (Water Supply Division, Health Services Bureau)”. It
provides the following guidance to heads of departments in charge of water supply
administration in each prefecture:
(1)
the public should refrain from drinking tap water that exceeds radiation safety limits;
(2)
tap water is safe for household use;
(3)
tap water intake should not be limited when an alternative source of water is unavailable.
Experts point out that boiling tap water is unlikely to reduce its content of radioactive
iodine.
2. Effects of radiation exposure
(1) Health effects of radiation exposure
The cumulative radiation dose is obtained by multiplying radiation dose per unit by
time. The website of the Cabinet Office of the Government of Japan explains it as
follows: even if a person remains for six hours in an area where the radiation level
is 100 µSv/hr, the cumulative radiation dose is only 600 µSv/hr. In comparison, we
are exposed to 2400 µSv of radiation per year from natural sources of radiation, including
radionuclides in the environment and cosmic rays, according to a 2008 UNSCEAR report.*1
The MEXT website, which presents data from monitoring posts outside the 20-kilometer
exclusion zone around the Fukushima I nuclear power plant, also gives examples of
typical radiation doses from various everyday sources.
The radiation levels detected by the monitoring posts were low, as were concentrations
of radionuclides. Therefore, as long as the current situation does not materially
change, the cumulative dose is so low that acute radiation effects will not develop
even if residents are exposed to radiation. In addition, the possibility of late effects,
which appear after many years, is negligible when compared to differences in health
risks among individuals with different lifestyles. Needless to say, there is no threat
of radiation exposure from housing evacuees.
The websites of the National Institute of Radiological Sciences and Radiation Effects
Association present detailed information on the health effects of radiation. Studies
of atomic bomb survivors in Hiroshima and Nagasaki indicate that a single exposure
to 1 million µSv (= 1 Sv) of radiation increases cancer risk by 60%. This increase
in risk is similar to that observed between nonsmokers and smokers. The effects of
radiation exposures that residents have received to date as a result of the Fukushima
power plant accident are expected to be much lower.*2
(2) Effect on the thyroid gland
Exposure to radionuclides such as radioactive I-131 through respiration and intake
of water and food is of considerable concern. This is referred to as internal exposure,
and radioactive iodines absorbed by the thyroid and its neighboring tissue can damage
the thyroid gland. Because the half-life of I-131 is 8 days, the radiation exposure
decreases day by day even if the radionuclides are inside the body. The most worrisome
health effect of such radiation is thyroid cancer. Fortunately, thyroid cancer is
usually not aggressive, and the survival rate is much higher than that of most cancers
(http://ganjoho.jp/public/index.html).
Administration of stable non-radioactive iodine is useful for preventing the effects
of radioactive iodine. However, it should be carefully administered and expert advice
is strongly recommended. Additional information is available in the document entitled
“Understanding administration of stable iodine during nuclear emergencies” prepared
by the Nuclear Safety Commission of Japan (http://www.nsc.go.jp/bousai/page3/houkoku02.pdf).
Radiation doses below 100 000–200 000 µSv are usually regarded as low. Exposure to
radiation from a source outside the body is called external exposure. External exposures
at doses higher than the low-dose range increase the risk of thyroid cancer. However,
this increase is mainly limited to children, and there is no clear evidence of increased
risk among adults. It should also be noted that the effect of internal exposure is
less well understood than that of external exposure. The 2006 UNSCEAR report indicated
that “in the last few years, information about 131I exposures has improved; however,
the thyroid cancer risk from 131I exposure is still not adequately quantified.”*3
(3) Effects of low-dose radiation exposure
The present accident resulted in internal exposure from radioactive iodines and other
radionuclides, as well as external exposures. However, as of March 24, it is expected
that the resident exposure will remain in the low-dose range. It should be noted,
however, that continuous monitoring is necessary. Low-dose radiation exposure does
not cause acute health effects. There have been many epidemiological studies of the
late effects, including cancer, in Japan and other countries. However, none has shown
clear evidence that low-dose radiation exposure increases the risk of cancer or other
diseases.
3. Concluding remarks
To evaluate the health effects of radiation, it is necessary to conduct epidemiological
studies and obtain accurate data on humans. However, accurate evaluation of low-dose
radiation exposure requires monitoring 100 000 or more people for at least 10 years.
For some dose distributions, an even larger study might be necessary. Therefore, conducting
an epidemiological study to evaluate the effects of low-dose exposure is not a simple
task. To date, such studies have produced no clear evidence regarding the health effects
of low-dose radiation exposure.*4 To reach a definitive conclusion, it will be necessary
to continue or expand ongoing studies or initiate new studies and collect information
for extensive evaluation.
An accurate understanding of the effects of radiation on humans is necessary to develop
and implement countermeasures to minimize the health effects that might be associated
with radiation exposure. If exposed persons have exaggerated ideas of the health effects
of radiation, they might suffer undue distress due to their unnecessary concern. In
addition, if residents do not understand the effects of radiation, others in the area
affected by a nuclear disaster might be treated unfairly or ostracized.
To avoid such situations and reassure residents, it will be necessary to conduct continuous
health check-ups of those exposed to radiation. Finally, the Japan Epidemiological
Association plans to educate citizens on the effects of radiation by providing them
with relevant information and by collaborating with future epidemiological studies.
*1
The 2006 UNSCEAR report estimated common sources of and exposure to natural radiation,
as follows:
Direct ionizing and photon component: 280 µSv
Neutron component: 100 µSv
Cosmogenic radionuclides: 10 µSv
External terrestrial radiation: 480 µSv
Uranium and thorium series: 6 µSv
Radon (222Rn): 1150 µSv
Thoron (220Rn): 100 µSv
Ingestion of 40K: 170 µSv
Ingestion of uranium and thorium series: 120 µSv
Total: approximately 2400 µSv
*2
This prediction is based on data from the 2006 UNSCEAR report, which relied on a review
of results from epidemiological and other relevant studies.
*3
The 2008 UNSCEAR report made the following points:
(1)
The thyroid gland is highly sensitive to the carcinogenic effects of external radiation
exposure during childhood.
(2)
Age at exposure is an important modifier of risk, and a very strong trend of decreasing
risk with increasing age at exposure was observed in most studies.
(3)
Although thyroid cancer is more frequent among women, sex differences with respect
to radiation risk are unclear.
(4)
Among persons exposed during childhood, the risks remain elevated throughout life,
although some data suggest that the risk begins to decline at about 20 years after
exposure.
(5)
The carcinogenic effects of 131I are less well understood. Most epidemiological studies
of medical exposures have shown little risk after exposure to a wide range of dose
levels; however, most of these studies were of adult exposures.
(6)
A follow-up study of persons who lived near the Hanford nuclear facility in the United
States when they were children showed no evidence of an association between 131I dose
and thyroid cancer risk.
(7)
In contrast, results from studies of people exposed as a result of the Chernobyl accident
showed that exposure to radioactive iodine during early childhood was significantly
linked with the risk of developing thyroid cancer. The risk appeared to be modified
by dietary intake of stable iodine. As was the case for data on external low-LET (Linear
Energy Transfer) radiation exposure, data from the Chernobyl accident studies suggest
that risk decreases with increasing age at exposure.
*4
On the effects of internal exposure from radionuclides, the UNSCEAR 2010 report to
the UN General Assembly stated: “Valuable information on the long-term low-dose exposures
to internally incorporated radionuclides has been provided by epidemiological studies
of the health of workers at the Mayak nuclear complex in the southern Urals of the
Russian Federation, and of the population near the Techa River whose exposure was
due to radioactive discharges from that facility. Overall, the cancer risk estimates
from these studies do not differ significantly from those obtained from the studies
of the atomic-bombing survivors in Japan.”
The report also discussed studies conducted in areas with high levels of background
radiation in India and China, about which the report stated: “By contrast, studies
on human populations living in areas with elevated natural background radiation in
China and India do not indicate that radiation at such levels increases the risk of
cancer.”
Indeed, in Kerala, India, there are areas where terrestrial gamma radiation levels
are as high as 10 000 µSv/yr (thus, over a period of 50 years, the total dose would
be 500 000 µSv). In those areas, more than 10 000 people have lived for many generations.