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      Safety and toxicokinetics of intravenous liposomal amphotericin B (AmBisome) in beagle dogs.

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      Journal: Pharmaceutical Research

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          Abstract

          Amphotericin B (AmB) in small, unilamellar liposomes (AmBisome) has an improved therapeutic index, and altered pharmacokinetics. The repeat-dose safety and toxicokinetic profiles of AmBisome were studied at clinically relevant doses.

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          PubMed ID:: 10571274
          DOI:: 10.1023/A:1018997730462

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