PAGE-B predicts the risk of developing hepatocellular carcinoma in Caucasians with chronic hepatitis B on 5-year antiviral therapy.

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Abstract

Risk scores for hepatocellular carcinoma (HCC) developed in Asians offer poor-moderate predictability in Caucasian patients with chronic hepatitis B (CHB). This nine center cohort study aimed to develop and validate an accurate HCC risk score in Caucasian CHB patients treated with the current oral antivirals, entecavir/tenofovir.

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Author and article information

Journal

Journal ID (iso-abbrev): J. Hepatol.

Title: Journal of hepatology

ISSN (Electronic): 1600-0641

ISSN (Print): 0168-8278

Publication date (Electronic): Apr 2016

Volume: 64

Issue: 4

Affiliations

[1 ] Department of Gastroenterology, School of Medicine, National and Kapodistrian University of Athens, Laiko General Hospital, Athens, Greece; 2nd Department of Internal Medicine, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece. Electronic address: gepapath@med.uoa.gr.

[2 ] Department of Internal Medicine, Thessalia University Medical School, Larissa, Greece.

[3 ] Department of Hygiene, Epidemiology & Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

[4 ] Department of Gastroenterology, University of Ankara Medical School, Ankara, Turkey.

[5 ] Hospital General Universitario Valle Hebron and Ciberehd, Barcelona, Spain.

[6 ] 4th Department of Internal Medicine, Αristotle University of Thessaloniki Medical School, Thessaloniki, Greece.

[7 ] Hospital U Puerta de Hierro, IDIPHIM CIBERehd, Madrid, Spain.

[8 ] Department of Gastroenterology & Hepatology, ErasmusMC, Rotterdam, Netherlands.

[9 ] 2nd Department of Internal Medicine, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

[10 ] Division of Gastroenterology and Hepatology, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, Milano, Italy.

[11 ] Department of Gastroenterology, School of Medicine, National and Kapodistrian University of Athens, Laiko General Hospital, Athens, Greece.

[12 ] Department of Gastroenterology & Hepatology, ErasmusMC, Rotterdam, Netherlands; Liver Clinic, Toronto Western & General Hospital, University Health Network, Toronto, ON, Canada.

Article

Publisher Item ID: S0168-8278(15)00795-3

DOI: 10.1016/j.jhep.2015.11.035

PubMed ID: 26678008

SO-VID: 9a53ebd9-61e2-4967-9864-95edaf9575fb

History

Keywords: Entecavir,Hepatitis B,Hepatocellular carcinoma,Tenofovir

Data availability:

Keywords: Entecavir, Hepatitis B, Hepatocellular carcinoma, Tenofovir

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