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      A Comparative Study on the Prediction of Occupational Diseases in China with Hybrid Algorithm Combing Models

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          Abstract

          Occupational disease is a huge problem in China, and many workers are under risk. Accurate forecasting of occupational disease incidence can provide critical information for prevention and control. Therefore, in this study, five hybrid algorithm combing models were assessed on their effectiveness and applicability to predict the incidence of occupational diseases in China. The five hybrid algorithm combing models are the combination of five grey models (EGM, ODGM, EDGM, DGM, and Verhulst) and five state-of-art machine learning models (KNN, SVM, RF, GBM, and ANN). The quality of the models were assessed based on the accuracy of model prediction as well as minimizing mean absolute percentage error (MAPE) and root-mean-squared error (RMSE). Our results showed that the GM-ANN model provided the most precise prediction among all the models with lowest mean absolute percentage error (MAPE) of 3.49% and root-mean-squared error (RMSE) of 1076.60. Therefore, the GM-ANN model can be used for precise prediction of occupational diseases in China, which may provide valuable information for the prevention and control of occupational diseases in the future.

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          Introduction to grey system theory

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            Grey system theory-based models in time series prediction

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              The circadian profile of epilepsy improves seizure forecasting.

              It is now established that epilepsy is characterized by periodic dynamics that increase seizure likelihood at certain times of day, and which are highly patient-specific. However, these dynamics are not typically incorporated into seizure prediction algorithms due to the difficulty of estimating patient-specific rhythms from relatively short-term or unreliable data sources. This work outlines a novel framework to develop and assess seizure forecasts, and demonstrates that the predictive power of forecasting models is improved by circadian information. The analyses used long-term, continuous electrocorticography from nine subjects, recorded for an average of 320 days each. We used a large amount of out-of-sample data (a total of 900 days for algorithm training, and 2879 days for testing), enabling the most extensive post hoc investigation into seizure forecasting. We compared the results of an electrocorticography-based logistic regression model, a circadian probability, and a combined electrocorticography and circadian model. For all subjects, clinically relevant seizure prediction results were significant, and the addition of circadian information (combined model) maximized performance across a range of outcome measures. These results represent a proof-of-concept for implementing a circadian forecasting framework, and provide insight into new approaches for improving seizure prediction algorithms. The circadian framework adds very little computational complexity to existing prediction algorithms, and can be implemented using current-generation implant devices, or even non-invasively via surface electrodes using a wearable application. The ability to improve seizure prediction algorithms through straightforward, patient-specific modifications provides promise for increased quality of life and improved safety for patients with epilepsy.

                Author and article information

                Contributors
                Journal
                Comput Math Methods Med
                Comput Math Methods Med
                CMMM
                Computational and Mathematical Methods in Medicine
                Hindawi
                1748-670X
                1748-6718
                2019
                29 September 2019
                : 2019
                : 8159506
                Affiliations
                1Department of Occupational and Environmental Health, College of Public Health, Xinjiang Medical University, Wulumuqi, Xinjiang 830011, China
                2Xinjiang Engineering Technology Research Center for Green Processing of Nature Product Center, Xinjiang Autonomous Academy of Instrumental Analysis, Urumqi, Xinjiang 830011, China
                3Department of Occupational Disease Prevention and Control, Wulumuqi Center for Disease Control and Prevention, Wulumuqi, Xinjiang 830026, China
                Author notes

                Academic Editor: Konstantin Blyuss

                Author information
                https://orcid.org/0000-0002-3798-0714
                Article
                10.1155/2019/8159506
                6791229
                9a5f0b11-026f-4014-8a1f-d76559db352e
                Copyright © 2019 Yaoqin Lu et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 10 May 2019
                : 3 August 2019
                : 27 August 2019
                Funding
                Funded by: National Natural Science Foundation of China
                Award ID: 81760581
                Funded by: Public Health and Preventive Medicine
                Funded by: 13th Five-Year Plan Key Subject of Xinjiang Uygur Autonomous Region
                Categories
                Research Article

                Applied mathematics
                Applied mathematics

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