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      A Comparison of Hemodynamic and Angiographic Indices of Left Ventricular Performance in Patients with Coronary Artery Disease

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          Abstract

          We compared ejection fraction, left ventricular end-diastolic pressure, cardiac index and the relation of left ventricular stroke work index to left ventricular end-diastolic pressure during rest and exercise in 60 patients with coronary artery disease. Left ventricular end-diastolic pressure was usually normal at rest (48/60) and abnormal during exercise (46/60) and did not correlate with ejection fraction. Cardiac index was insensitive, usually remaining normal until ejection fraction was < 0.40. Patients with a normal left ventricular stroke work index response to exercise had higher ejection fractions than those with an abnormal response (p < 0.05). However, 9 patients with normal ejection fractions had an abnormal exercise response. This may reflect loss of left ventricular reserve, abnormal compliance or clinically silent ischemia during exercise. Different indices of left ventricular performance may be widely disparate in coronary artery disease, and abnormalities are frequently apparent only during exercise.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1978
          1978
          31 October 2008
          : 63
          : 4
          : 220-236
          Affiliations
          University of Utah College of Medicine and Salt Lake Veterans Administration Hospital, Salt Lake City, Utah
          Article
          169901 Cardiology 1978;63:220–236
          10.1159/000169901
          657174
          © 1978 S. Karger AG, Basel

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          Page count
          Pages: 17
          Categories
          Original Paper

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