Formulas for Calculated Osmolarity and Osmolal Gap: A Study of Diagnostic Accuracy.

Lepeytre, Fanny; Ghannoum, Marc; Ammann, Hélène; Madore, Francois; Troyanov, Stéphan; Goupil, Remi; Bouchard, Josée

doi:10.1053/j.ajkd.2017.03.023

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Formulas for Calculated Osmolarity and Osmolal Gap: A Study of Diagnostic Accuracy.

Author(s): Fanny Lepeytre ¹ , Marc Ghannoum ² , Hélène Ammann ³ , François Madore ¹ , Stéphan Troyanov ¹ , Rémi Goupil ¹ , Josée Bouchard ⁴

Publication date (Electronic): Sep 2017

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation

Publisher: Elsevier BV

Keywords: Equation, diagnostic accuracy, ethanol, formula, glucose, osmolal gap (OG), osmolality, osmolarity, sodium, toxic alcohol, urea

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Abstract

The osmolal gap has been used for decades to screen for exposure to toxic alcohols. However, several issues may affect its reliability. We aimed to develop equations to calculate osmolarity with improved performance when used to screen for intoxication to toxic alcohols.

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Journal ID (iso-abbrev): Am. J. Kidney Dis.

Title: American journal of kidney diseases : the official journal of the National Kidney Foundation

Publisher: Elsevier BV

ISSN (Electronic): 1523-6838

ISSN (Print): 0272-6386

Publication date (Electronic): Sep 2017

Volume: 70

Issue: 3

Affiliations

[1 ] Division of Nephrology, Department of Medicine, Hôpital du Sacré-Cœur de Montréal, Faculty of Medicine, Université de Montréal, Montréal, Québec, Canada.

[2 ] Division of Nephrology, Department of Medicine, Verdun Hospital, Faculty of Medicine, Université de Montréal, Montréal, Québec, Canada.

[3 ] Department of Medical Biology, Hôpital du Sacré-Cœur de Montréal, Montréal, Québec, Canada.

[4 ] Division of Nephrology, Department of Medicine, Hôpital du Sacré-Cœur de Montréal, Faculty of Medicine, Université de Montréal, Montréal, Québec, Canada. Electronic address: josee.bouchard.1@umontreal.ca.

Article

Publisher Item ID: S0272-6386(17)30670-4

DOI: 10.1053/j.ajkd.2017.03.023

PubMed ID: 28578820

SO-VID: 9aa9fa90-fcae-4e14-bf78-d850e296f7cf

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Keywords: osmolarity,sodium,toxic alcohol,urea,Equation,diagnostic accuracy,ethanol,formula,glucose,osmolal gap (OG),osmolality

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Keywords: osmolarity, sodium, toxic alcohol, urea, Equation, diagnostic accuracy, ethanol, formula, glucose, osmolal gap (OG), osmolality

Formulas for Calculated Osmolarity and Osmolal Gap: A Study of Diagnostic Accuracy.

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Numerical Algebra, Matrix Theory, Differential-Algebraic Equations, and Control Theory

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