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      HIV-Related Stress and Life Chaos Mediate the Association Between Poverty and Medication Adherence Among People Living with HIV/AIDS.

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          Abstract

          HIV treatment depends on high-levels of antiretroviral therapy (ART) adherence, which is severely impeded by poverty. Men and women living with HIV infection (N = 92) completed computerized interviews of demographic and health characteristics, poverty markers, stressful life events, and life chaos, as well as unannounced pill counts to determine prospective medication adherence and medical record chart abstractions for HIV viral load. Poverty markers were associated with both stressors and chaos, and the direct effects of all three factors predicted ART non-adherence. The multiple mediation model showed that accounting for stressors and chaos resulted in a non-significant association between poverty markers and ART adherence. The indirect effect of poverty markers on adherence through life chaos was significant, whereas the indirect effect of poverty markers on adherence through stressors was not significant. Factors that render HIV-related stress and create chaos offer intervention targets that are more amenable to change than poverty itself.

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          Author and article information

          Journal
          J Clin Psychol Med Settings
          Journal of clinical psychology in medical settings
          Springer Nature
          1573-3572
          1068-9583
          Dec 2016
          : 23
          : 4
          Affiliations
          [1 ] Department of Psychological Sciences, University of Connecticut, 406 Babbidge Road, Storrs, CT, 06269, USA. seth.k@uconn.edu.
          [2 ] Department of Psychological Sciences, University of Connecticut, 406 Babbidge Road, Storrs, CT, 06269, USA.
          Article
          10.1007/s10880-016-9481-8
          10.1007/s10880-016-9481-8
          27873055
          9afda5a7-6fb5-4488-9ed9-15fa39f7a37d
          History

          Stress,Poverty,HIV/AIDS treatment,Medication adherence
          Stress, Poverty, HIV/AIDS treatment, Medication adherence

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