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      Strategies to Prevent Surgical Site Infections in Acute Care Hospitals

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          Abstract

          Previously published guidelines are available that provide comprehensive recommendations for detecting and preventing healthcare-associated infections. The intent of this document is to highlight practical recommendations in a concise format designed to assist acute care hospitals to implement and prioritize their surgical site infection (SSI) prevention efforts. Refer to the Society for Healthcare Epidemiology of America/Infectious Diseases Society of America “Compendium of Strategies to Prevent Healthcare-Associated Infections” Executive Summary and Introduction and accompanying editorial for additional discussion.

          1. Burden of SSIs as complications in acute care facilities.

          a. SSIs occur in 2%-5% of patients undergoing inpatient surgery in the United States.

          b. Approximately 500,000 SSIs occur each year.

          2. Outcomes associated with SSI

          a. Each SSI is associated with approximately 7-10 additional postoperative hospital days.

          b. Patients with an SSI have a 2-11 times higher risk of death, compared with operative patients without an SSI.

          i. Seventy-seven percent of deaths among patients with SSI are direcdy attributable to SSI.

          c. Attributable costs of SSI vary, depending on the type of operative procedure and the type of infecting pathogen; published estimates range from $3,000 to $29,000.

          i. SSIs are believed to account for up to $10 billion annually in healthcare expenditures.

          1. Definitions

          a. The Centers for Disease Control and Prevention National Nosocomial Infections Surveillance System and the National Healthcare Safety Network definitions for SSI are widely used.

          b. SSIs are classified as follows (Figure):

          i. Superficial incisional (involving only skin or subcutaneous tissue of the incision)

          ii. Deep incisional (involving fascia and/or muscular layers)

          iii. Organ/space

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          Most cited references51

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          Guideline for prevention of surgical site infection, 1999. Hospital Infection Control Practices Advisory Committee.

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            The efficacy of infection surveillance and control programs in preventing nosocomial infections in US hospitals.

            In a representative sample of US general hospitals, the authors found that the establishment of intensive infection surveillance and control programs was strongly associated with reductions in rates of nosocomial urinary tract infection, surgical wound infection, pneumonia, and bacteremia between 1970 and 1975-1976, after controlling for other characteristics of the hospitals and their patients. Essential components of effective programs included conducting organized surveillance and control activities and having a trained, effectual infection control physician, an infection control nurse per 250 beds, and a system for reporting infection rates to practicing surgeons. Programs with these components reduced their hospitals' infection rates by 32%. Since relatively few hospitals had very effective programs, however, only 6% of the nation's approximately 2 million nosocomial infections were being prevented in the mid-1970s, leaving another 26% to be prevented by universal adoption of these programs. Among hospitals without effective programs, the overall infection rate increased by 18% from 1970 to 1976.
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              The impact of surgical-site infections following orthopedic surgery at a community hospital and a university hospital: adverse quality of life, excess length of stay, and extra cost.

              To measure the impact of orthopedic surgical-site infections (SSIs) on quality of life, length of hospitalization, and cost. A pairwise-matched (1:1) case-control study within a cohort. A tertiary-care university medical center and a community hospital. Cases of orthopedic SSIs were prospectively identified by infection control professionals. Matched controls were selected from the entire cohort of patients undergoing orthopedic surgery who did not have an SSI. Matching variables included type of surgical procedure, National Nosocomial Infections Surveillance risk index, age, date of surgery, and surgeon. Quality of life, duration of postoperative hospital stay, frequency of hospital readmission, overall direct medical costs, and mortality rate. Fifty-nine SSIs were identified. Each orthopedic SSI accounted for a median of 1 extra day of stay during the initial hospitalization (P = .001) and a median of 14 extra days of hospitalization during the follow-up period (P = .0001). Patients with SSI required more rehospitalizations (median, 2 vs 1; P = .0001) and more total surgical procedures (median, 2 vs 1; P = .0001). The median total direct cost of hospitalizations per infected patient was $24,344, compared with $6,636 per uninfected patient (P = .0001). Mortality rates were similar for cases and controls. Quality of life was adversely affected for patients with SSI. The largest decrements in scores on the Medical Outcome Study Short Form 36 questionnaire were seen in the physical functioning and role-physical domains. Orthopedic SSIs prolong total hospital stays by a median of 2 weeks per patient, approximately double rehospitalization rates, and increase healthcare costs by more than 300%. Moreover, patients with orthopedic SSIs have substantially greater physical limitations and significant reductions in their health-related quality of life.
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                Author and article information

                Journal
                Infection Control & Hospital Epidemiology
                Infect. Control Hosp. Epidemiol.
                University of Chicago Press
                0899-823X
                1559-6834
                October 2008
                January 02 2015
                October 2008
                : 29
                : S1
                : S51-S61
                Article
                10.1086/591064
                18840089
                9bf0b2a3-9a4b-48a9-80f2-3b8821174998
                © 2008

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