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      Some in vitro Effects of Synthetic Thyrotrophin Releasing Factor on the Secretion of Thyroid Stimulating Hormone from the Anterior Pituitary Gland of the Domestic Fowl

      Neuroendocrinology

      S. Karger AG

      Thyrotrophin releasing factor, Thyrotrophin, Luteinizing hormone, Chicken, Hypothalamus

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          Abstract

          Chicken anterior pituitary glands were incubated in vitro with different doses of synthetic thyrotrophin releasing factor (TRF). The release of both thyroid stimulating hormone (TSH) and luteinizing hormone (LH) was then monitored. Relatively low doses of TRF (2 and 4 ng/ml) significantly increased the re-lease of TSH, whereas at a lower dose (1 ng/ml) and at a higher dose (20 ng/ml) no stimulation was observed. The secretion of LH remained unchanged by any TRF treatment. An acid extract of chicken hypothalami significantly increased the secretion of both LH and TSH from the bird pituitary tissue.

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          Author and article information

          Journal
          NEN
          Neuroendocrinology
          10.1159/issn.0028-3835
          Neuroendocrinology
          S. Karger AG
          0028-3835
          1423-0194
          1974
          1974
          20 March 2008
          : 15
          : 1
          : 1-9
          Affiliations
          Department of Animal Physiology and Nutrition, University of Leeds, Leeds
          Article
          122287 Neuroendocrinology 1974;15:1–9
          10.1159/000122287
          4212344
          © 1974 S. Karger AG, Basel

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          Page count
          Pages: 9
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          Paper

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