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      US Experience in Evaluation and Diagnosis of GH Therapy of Intrauterine Growth Retardation/Small-for-Gestational-Age Children

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          The potential role of exogenous GH in treating short children born small for gestational age (SGA) has been discussed since the early 1960s. Pivotal studies in Europe during the last 10 years have shown that GH treatment of short children born SGA during childhood and early puberty (1) normalizes stature, (2) increases final height above predicted height and (3) allows children to reach their target height. A study now under way in the USA will provide additional much needed data about efficacy and safety of GH treatment in intrauterine growth retardation/SGA.

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          Most cited references 6

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          Growth Hormone Treatment in Children with Short Stature Born Small for Gestational Age: 5-Year Results of a Randomized, Double-Blind, Dose-Response Trial

           T. Sas (1999)
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            Growth Hormone Treatment of Short Children Born Small for Gestational Age: Growth Responses with Continuous and Discontinuous Regimens Over 6 Years

             F de Zegher (2000)
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              High-dose growth hormone treatment of short children born small for gestational age

               F de Zegher (1996)

                Author and article information

                Horm Res Paediatr
                Hormone Research in Paediatrics
                S. Karger AG
                November 2002
                17 November 2004
                : 58
                : Suppl 3
                : 27-29
                Department of Pediatrics, Division of Pediatric Endocrinology, Albert Einstein College of Medicine, Children’s Hospital at Montefiore, Bronx, N.Y., USA
                66479 Horm Res 2002;58(suppl 3):27–29
                © 2002 S. Karger AG, Basel

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                Page count
                References: 21, Pages: 3
                GH in Children


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