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      Musculoskeletal Symptoms in Hemodialysis Patients and their Effect on Health-Related Quality of Life

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          Abstract

          Background/Aims: Hemodialysis (HD) represents one of the most commonly used modalities as a renal replacement therapy. Health-related quality of life (HRQoL) is much lower in HD patients than general population. Musculoskeletal (MSK) symptoms are one of the most important health problems that affect patients on maintenance HD. The main purpose of this study was to investigate the association between MSK symptoms and HRQoL among HD patients. Methods: The study was carried out on 200 patients with chronic renal failure on chronic HD at different nephrology units in Egypt. They completed the Arabic version of the Kidney Disease and Quality of Life-Short Form 1.3 Questionnaire and answered the questions of MSK discomfort form based on the Nordic MSK Questionnaire. Results: The mean age of the patients was 50.6 years, 61% were males. Of the 200 HD patients, 180 patients (90%) had MSK manifestations. The most commonly affected part was knee joint (51.5%). Regarding HRQoL, patients with MSK symptoms had significantly lower scores than did patients without on the physical role ( p = 0.035), pain domain ( p = 0.003), general health ( p = 0.017), quality of social interaction ( p = 0.046), and sleep domain ( p = 0.022). Conclusion: MSK manifestations have a negative impact on HRQoL in HD patients. So, early identification and treatment are highly recommended.

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          Author and article information

          Journal
          BPU
          Blood Purif
          10.1159/issn.0253-5068
          Blood Purification
          S. Karger AG
          0253-5068
          1421-9735
          2020
          May 2020
          10 January 2020
          : 49
          : 3
          : 289-294
          Affiliations
          aNephrology Unit, Department of Internal Medicine, Nabarouh Central Hospital, Mansoura University, Mansoura, Egypt
          bRheumatology and Immunology Unit, Department of Internal Medicine, Faculty of Medicine, Mansoura University Hospital, Mansoura University, Mansoura, Egypt
          cDepartment of Public Health and Community Medicine, Faculty of Medicine, Mansoura University, Mansoura, Egypt
          Author notes
          *Samar Tharwat, Rheumatology and Immunology Unit, Department of Internal Medicine, Mansoura Faculty of Medicine, Mansoura University Hospital, Mansoura University, El Gomhouria St, Mit Khamis WA Kafr Al Mougi, 35511 Mansoura (Egypt), E-Mail samartharwat2000@yahoo.com
          Article
          504038 Blood Purif 2020;49:289–294
          10.1159/000504038
          31927539
          © 2020 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Figures: 1, Tables: 4, Pages: 6
          Categories
          Research Article

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